Dextran T10 (MW 10,000)
Based on 1 Customer Validation
Dextran T10 (MW 10,000) (Dextran 10) is a dehydrated glucose polymer with an average molecular weight of 10,000. Dextran T10 (MW 10,000) is composed of repeated glucose units, and it has abundant hydroxyl (-OH) groups, which can be used as a natural "magnetic marker" for chemical exchange saturation transfer (CEST) MRI imaging.
For research use only. We do not sell to patients.
- CAS No.: 9004-54-0
- Formula: (C6H10O5)n
- Molecular Weight:8000-12000
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Dextran T10 (MW 10,000) (375 mg/kg, i.v., single dose) serves as a nanoscale chemical exchange saturation transfer (CEST) magnetic resonance imaging probe, generating a strong dexCEST contrast, and successfully characterizing the tumor vascular permeability of mice with subcutaneous colon tumors CT26[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 9004-54-0
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Appearance Solid
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Molecular Weight 8000-12000
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Formula (C6H10O5)n
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Color White to off-white
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SMILES
[Dextran T10 (MW 10,000)]
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Synonyms
Dextran 10; Dextran D10; Dextran T10(MW 8000-12000)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 200 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[2]. Miyamoto H, et al. Influence of Liver Intoxication by Carbon Tetrachloride or D-Galactosamine on Absorption of Fluorescein Isothiocyanate-Dextran-10 and Other Marker Compounds with Different Molecular Weights from the Rat Liver Surface. Biol Pharm Bull. 2020;43(2):319-324. [Content Brief]
[3]. Li Y, et al. Characterization of tumor vascular permeability using natural dextrans and CEST MRI. Magn Reson Med. 2018 Feb;79(2):1001-1009. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dextran T10 (MW 10,000) Related Classifications
HY-112624L Related Classifications
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