Dextran T20 (MW 20,000) (Synonyms: Dextran 20; Dextran D20; Dextran T20(MW 16000-24000))

Name: Dextran T20 (MW 20,000)
Brand: MedChemExpress
SKU: HY-112624U
Rating: 4.5 (1 reviews)

Cat. No.: HY-112624U: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Dextran T20 (Dextran 20; Dextran D20) (MW 20,000) is a dehydrated glucose polymer with an average molecular weight of 20,000. Dextran T20 (MW 20,000) has excellent biodegradability and good biocompatibility, and can be used as a gene delivery vector, an immune adjuvant carrier, and a hemoglobin stabilizer.

For research use only. We do not sell to patients.

Dextran T20 (MW 20,000) Chemical Structure

CAS No. : 9004-54-0

Size	Stock	Quantity
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Dextran T20 (MW 20,000):

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Dextran T20 (MW 20,000) is covalently bound to bovine hemoglobin, forming a stable dextransome-hemoglobin complex (dex20-bHb). dex20-bHb significantly reduces the self-oxidation rate of hemoglobin by enhancing the tetramer stability and oxygen affinity of hemoglobin¹.
Dextran T20 (MW 20,000) can be used to construct cytosine-phosphate-guanine (CpG)-right glycolic acid conjugates. These conjugates can significantly enhance the uptake by antigen-presenting cells and trigger a strong immune response, but their relatively small size may not be sufficient to provide strong resistance to nucleases^[2].
Dextran T20 (MW 20,000) is covalently bound to a cationic peptide R5H5 to form a right-handed dextran-peptide hybrid (Dex-R5H5), which is used for the safe and effective delivery of genes (plasmid DNA)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

16000-24000

Formula

(C₆H₁₀O₅)_n

CAS No.

9004-54-0

Appearance

Solid

Color

White to off-white

SMILES

[Dextran T20 (MW 20,000)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic)

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Select Batch:

Data Sheet (269 KB) SDS (254 KB)

COA (243 KB)

Handling Instructions (2659 KB)

References

[1]. Zhang J, et al. Conjugation with 20 kDa dextran decreases the autoxidation rate of bovine hemoglobin. Artif Cells Nanomed Biotechnol. 2018 Nov;46(7):1436-1443. [Content Brief]

[2]. Nguyen HV, et al. Effect of carrier molecular weight on physicochemical properties and the in vitro immune-stimulatory activity of the CpG-dextran conjugates. Int J Pharm. 2022 Nov 5;627:122236. [Content Brief]

[3]. Tang Q, et al. Dextran-peptide hybrid for efficient gene delivery. Langmuir. 2014 May 13;30(18):5202-8. [Content Brief]

Dextran T20 (MW 20,000) Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dextran T20 (MW 20,000)9004-54-0Dextran 20 Dextran D20Dextran T20(MW 16000-24000)Dextran20Dextran-20Dextran D20Dextran D 20Dextran D-20Biochemical Assay ReagentsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Dextran T20 (MW 20,000) (Synonyms: Dextran 20; Dextran D20; Dextran T20(MW 16000-24000))

Customer Review

Other Forms of Dextran T20 (MW 20,000):

Dextran T20 (MW 20,000) Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Dextran T20 (MW 20,000) Related Antibodies

Molarity Calculator

Dilution Calculator

Dextran T20 (MW 20,000) Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report