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  4. Dextran T1 (MW 1,000)

Dextran T1 (MW 1,000)  (Synonyms: Dextran 1; Dextran D1; Dextran T1(MW 800-1200))

Cat. No.: HY-112624A
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Dextran T1 (Dextran 1; Dextran D1) (with a molecular weight of 1,000) is a dehydrated glucose polymer with an average molecular weight of 1,000. Dextran T1 (MW 1,000) has excellent biodegradability and biocompatibility, and can be used as a nanobody carrier scaffold and a freeze-drying protectant. Dextran T1 (MW 1,000) promotes the retention of circulating tumor cells in the capillary bed.

For research use only. We do not sell to patients.

Dextran T1 (MW 1,000)

Dextran T1 (MW 1,000) Chemical Structure

CAS No. : 9004-54-0

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Description

Dextran T1 (Dextran 1; Dextran D1) (with a molecular weight of 1,000) is a dehydrated glucose polymer with an average molecular weight of 1,000. Dextran T1 (MW 1,000) has excellent biodegradability and biocompatibility, and can be used as a nanobody carrier scaffold and a freeze-drying protectant. Dextran T1 (MW 1,000) promotes the retention of circulating tumor cells in the capillary bed[1][2][3].

In Vitro

Dextran T1 (MW 1,000) exhibits protective effects during the freeze-drying process of Aviscumine (a recombinant protein). At a concentration of 8%, it can form a completely amorphous freeze-dried cake, thereby avoiding the damage to the protein caused by the phase separation of crystals[1].
Dextran T1 (MW 1,000) can be used as a scaffold to construct a nanobody-drug conjugate (NBBC-Dex1-PS). The NBBC-Dex1-PS can penetrate into the interior of the tumor sphere, and its penetration behavior is similar to that of the conjugates using larger molecular weight Dextran (5k, 10k)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dextran T1 (MW 1,000) Related Antibodies
In Vivo

Dextran T1 (MW 1,000) (0.75 mL/100 g, i.v., single dose) significantly increased the retention of tumor cells in the lungs and liver3.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

800-1200

Formula

(C6H10O5)n
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Dextran T1 (MW 1,000)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This equation is commonly abbreviated as: C1V1 = C2V2

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

SDS (393 KB)

COA (242 KB)

Handling Instructions (2659 KB)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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