Dextran T1 (MW 1,000)
Based on 1 Customer Validation
Dextran T1 (Dextran 1; Dextran D1) (with a molecular weight of 1,000) is a dehydrated glucose polymer with an average molecular weight of 1,000. Dextran T1 (MW 1,000) has excellent biodegradability and biocompatibility, and can be used as a nanobody carrier scaffold and a freeze-drying protectant. Dextran T1 (MW 1,000) promotes the retention of circulating tumor cells in the capillary bed.
For research use only. We do not sell to patients.
- CAS No.: 9004-54-0
- Formula: (C6H10O5)n
- Molecular Weight:800-1200
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Dextran T1 (MW 1,000) exhibits protective effects during the freeze-drying process of Aviscumine (a recombinant protein). At a concentration of 8%, it can form a completely amorphous freeze-dried cake, thereby avoiding the damage to the protein caused by the phase separation of crystals[1].
Dextran T1 (MW 1,000) can be used as a scaffold to construct a nanobody-drug conjugate (NBBC-Dex1-PS). The NBBC-Dex1-PS can penetrate into the interior of the tumor sphere, and its penetration behavior is similar to that of the conjugates using larger molecular weight Dextran (5k, 10k)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-54-0
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Appearance Solid
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Molecular Weight 800-1200
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Formula (C6H10O5)n
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Color White to off-white
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SMILES
[Dextran T1 (MW 1,000)]
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Synonyms
Dextran 1; Dextran D1; Dextran T1(MW 800-1200)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Gloger O, et al. Lyoprotection of aviscumine with low molecular weight dextrans. Int J Pharm. 2003 Jul 9;260(1):59-68. [Content Brief]
[2]. Bitsch P, et al. Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids. Pharmaceutics. 2023 Sep 22;15(10):2374. [Content Brief]
[3]. Skolnik G, et al. The influence of trauma, Dextran 1000, and Dextran 40 on the lodgement of circulating tumor cells. J Cancer Res Clin Oncol. 1980;97(3):241-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dextran T1 (MW 1,000) Related Classifications
HY-112624A Related Classifications
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