Dextran T0.8 (MW 800)
Based on 1 Customer Validation
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
For research use only. We do not sell to patients.
- CAS No.: 9004-54-0
- Formula: (C6H10O5)n
- Molecular Weight:640-960
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Dextran T0.8 (MW 800) (1-500 μg/mL; 48 h) shows no significant in vitro toxicity to HeLa cells[2].
Dextran T0.8 (MW 800) (2-8% w/v sucrose system; 30°C, 8 h) shows enhanced coagulation effect on skim milk with increasing sucrose concentration, and has the potential to be used as a food additive to improve the texture of dairy products[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-54-0
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Appearance Solid
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Molecular Weight 640-960
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Formula (C6H10O5)n
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Color White to off-white
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SMILES
[Dextran T0.8 (MW 800)]
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Synonyms
Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Chen F, et al. Preparation and application of dextran and its derivatives as carriers. Int J Biol Macromol. 2020 Feb 15;145:827-834. [Content Brief]
[2]. Tingirikari JM, et al. Structural and biocompatibility properties of dextran from Weissella cibaria JAG8 as food additive. Int J Food Sci Nutr. 2014 Sep;65(6):686-91. [Content Brief]
[3]. Giorgi-Coll S, et al. Dextran 500 Improves Recovery of Inflammatory Markers: An In Vitro Microdialysis Study. J Neurotrauma. 2020 Jan 1;37(1):106-114. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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