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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
glucose-6-phosphatase
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "glucose-6-phosphatase" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N12445
CAS No.: 19254-30-9
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Cat. No.: HY-W089800
CAS No.: 18829-56-6
Synonyms: trans-2-Nonen-1-al
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trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .
Cat. No.: HY-P5489
CAS No.: 849069-99-4
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Cat. No.: HY-125539
CAS No.: 16891-85-3
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Cat. No.: HY-W197205
CAS No.: 380173-90-0
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SL010110 is an anti-hyperglycemic agent. SL010110 potently inhibits gluconeogenesis by inhibiting SIRT2, activating p300, and subsequently promoting PEPCK1 degradation. SL010110 downregulates the protein level of PEPCK1 without affecting the gene expressions of PEPCK, glucose-6-phosphatase, and fructose-1,6-bisphosphatase. SL010110 significantly improves glucose homeostasis in type 2 diabetic (T2D) mice model. SL010110 can be used for T2D research .
Cat. No.: HY-16443
CAS No.: 173534-37-7
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S-4048 is a glucose-6-phosphate translocase modulator and hypoglycemic agent. S-4048 is taken up by hepatocytes via OATP-1 and is rapidly eliminated via the hepatobiliary system in rats. S-4048 blocks glucose-6-phosphate translocase, prevents glucose-6-phosphate from entering the endoplasmic reticulum, and thereby interferes with the glucose-6-phosphatase system (i.e., the final step of hepatic gluconeogenesis and glycogenolysis) to regulate hepatic glucose production. S-4048 completely inhibits glucose production from pyruvate in GLUT2-deficient hepatocytes without affecting the release of cytoplasmic glucose. S-4048 effectively reduces blood glucose levels in rats and has been used in studies related to type 2 diabetes .
Cat. No.: HY-P2801A
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Glucose-6-Phosphatase, Rabbit (EC 3.1.3.9) is an enzyme that hydrolyzes glucose-6-phosphate, resulting in the creation of a phosphate group and free glucose. Glucose is then exported from the cell via glucose transporter membrane proteins.
Cat. No.: HY-N14462
CAS No.: 355840-22-1
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Cat. No.: HY-16442
CAS No.: 160341-09-3
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S-3483, a Chlorogenic acid (HY-N0055) derivative, is a reversible, linear competitive glucose-6-phosphatase (Glc-6-Pase) system inhibitor. S-3483 inhibits Glc-6-Pase with a Ki 129 nM in rat liver microsomes. S-3483 specifically inhibits Glc-6-P transporter of renal and liver microsomes .
Cat. No.: HY-W834690
CAS No.: 237402-29-8
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G6Pase catalytic enzyme-IN-1 is a competitive inhibitor of glucose-6-phosphatase catalytic enzyme. G6Pase catalytic enzyme-IN-1 has an IC50 of 10 μM in pig liver microsomes. G6Pase catalytic enzyme-IN-1 can be used in studies related to type 2 diabetes .
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N-Octylmaleimide is an alkylmaleimide, which can inhibit rat liver glucose 6-phosphatase .
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Mebanazine is a potent monoamine oxidase (MAO) inhibitor. Mebanazine can be used in research of depression .
Cat. No.: HY-P702035
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC37A4; Sugar-Phosphate Exchange Protein 4; Prev. G6PT1; glucose-6-Phosphate Translocase; Prev. G6PT3; glucose-5-Phosphate Transporter; Prev. G6PT2; TRG-19; G6PT; glucose-6-phosphatase, Transport (Phosphate/Pyrophosphate) Protein 2; glucose-6-Phosphate E
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
