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Results for "

licorice

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) AMPK (1) Bacterial (4) Cytochrome P450 (1) Estrogen Receptor/ERR (1) Fungal (1) HIV (1) Keap1-Nrf2 (2) Monoamine Oxidase (1) Oxidative Phosphorylation (1) PPAR (1) Proteasome (1) Tyrosinase (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Infection (6) Inflammation/Immunology (5) Metabolic Disease (5) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6980

Licorice glycoside C2 1 Publications Verification	HIV	Infection Cancer
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .

HY-N6911

Licorice-saponin H2

(18β,20α)-Glycyrrhizic acid
Others Metabolic Disease

Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin from Glycyrrhiza uralensis Fischer .
HY-N6982

Licoricesaponin A3

Others Metabolic Disease

Licoricesaponin A3 is a terpenoid saponin identified from licorice .

Licorice-saponin H2 (18β,20α)-Glycyrrhizic acid	Others	Metabolic Disease
Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin from Glycyrrhiza uralensis Fischer .

Licoricesaponin A3	Others	Metabolic Disease
Licoricesaponin A3 is a terpenoid saponin identified from licorice .

HY-N11034

*24-Hydroxy-licorice-saponin A3*	Others	Others
24-Hydroxy-licorice-saponin A3 is an oleanane-type triterpene saponin (OTS). 24-Hydroxy-licorice-saponin A3 can be isolated from G. uralensis. .

HY-N7372

Licoisoflavanone

Others Others

Licoisoflavanone is the isoflavonoid compound isolated from Sinkiang licorice root (Glycyrrhiza) .

Licoisoflavanone	Others	Others
Licoisoflavanone is the isoflavonoid compound isolated from Sinkiang licorice root (Glycyrrhiza) .

HY-N11771

Glyurallin B	Others	Others
Glyurallin B is a flavonoid, that can be isolated from licorice (Glycyrrhiza inflata and Glycyrrhiza uralensis). Glyurallin B shows ABTS ⁺ radical scavenging activity and the inhibitory activity on lipid peroxidation, with EC₅₀ values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectivley .

HY-142101

3,4-Didehydroglabridin	Others	Inflammation/Immunology
3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury .

HY-N9329

Glicoricone	Monoamine Oxidase Estrogen Receptor/ERR	Metabolic Disease
Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC₅₀ of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity .

HY-N4113

Glycycoumarin	Keap1-Nrf2 AMPK	Cancer
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-N2417

Stearyl glycyrrhetinate	Bacterial	Infection
Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects .

HY-N11975

Glycyrrhizin-6′,6′′-dimethylester	Others	Others
Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .

HY-N11976

Glycyrrhizin-6′′-methylester	Others	Others
Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .

HY-N1471

Liquiritin apioside

1 Publications Verification

Liquiritin apioside, a main flavonoid component of licorice, possesses antitussive effects .
HY-N6804

Diammonium Glycyrrhizinate

Others Inflammation/Immunology Cancer

Diammonium Glycyrrhizinate, isolated from the licorice root, is a widely used anti-inflammatory agent .
HY-N11111

Glycyrrhizin-6'-methylester

Others Others

Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .

Liquiritin apioside 1 Publications Verification
Liquiritin apioside, a main flavonoid component of licorice, possesses antitussive effects .

Diammonium Glycyrrhizinate	Others	Inflammation/Immunology Cancer
Diammonium Glycyrrhizinate, isolated from the licorice root, is a widely used anti-inflammatory agent .

Glycyrrhizin-6'-methylester	Others	Others
Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .

HY-N3947

Glepidotin B	Bacterial	Infection
Glepidotin B is a dihydroflavonol compound isolated from the extracts of American licorice, Glycyrrhiza lepidota (Leguminosae). Glepidotin B is an antimicrobial agent .

HY-N3943

Glabrene	Tyrosinase	Neurological Disease
Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC₅₀ of 3.5 μM .

HY-N3386

Licoricone	Bacterial	Infection
Licoricone is an flavonoid extracted from licorice, exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains .

HY-N3960

Glycyrin	PPAR Bacterial	Infection Metabolic Disease
Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity .

HY-N0765

Isoliquiritin 1 Publications Verification	Fungal	Infection Neurological Disease Inflammation/Immunology
Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .

HY-W009731

Dibenzoylmethane	Keap1-Nrf2	Metabolic Disease Cancer
Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2 .

HY-N4193

Glabrol	Acyltransferase	Cardiovascular Disease
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ value of 24.6 μM for rat liver microsomal ACAT activity .

HY-Y0543

5-Methylfurfural 1 Publications Verification
5-Methylfurfural is a naturally occurring substance, found in cigarette smoke condensate, licorice essential oil, stored dehydrated orange powder, baked potato flour, volatile compounds of roast beef, aroma concentrate of sponge cake. bread and in coffee, tea and cocoa . A flavoring agent.

HY-N2920

β-Amyrenonol 11-Oxo-β-amyrin	Cytochrome P450	Inflammation/Immunology Cancer
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

HY-N7056

4'-Hydroxychalcone	Oxidative Phosphorylation Proteasome	Inflammation/Immunology Cancer
4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria .

Licorice glycoside C2 1 Publications Verification	Infection Structural Classification Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	HIV
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .

Licorice-saponin H2 (18β,20α)-Glycyrrhizic acid	Triterpenes Classification of Application Fields Leguminosae Terpenoids Source classification Metabolic Disease Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Others
Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin from Glycyrrhiza uralensis Fischer .

Licoricesaponin A3	Triterpenes Classification of Application Fields Leguminosae Terpenoids Source classification Metabolic Disease Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Others
Licoricesaponin A3 is a terpenoid saponin identified from licorice .

*24-Hydroxy-licorice-saponin A3*	Triterpenes Structural Classification Leguminosae Terpenoids Source classification Plants Glycyrrhiza uralensis Fisch.	Others
24-Hydroxy-licorice-saponin A3 is an oleanane-type triterpene saponin (OTS). 24-Hydroxy-licorice-saponin A3 can be isolated from G. uralensis. .

Licoisoflavanone	Flavonoids Classification of Application Fields Leguminosae Isoflavanones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Others
Licoisoflavanone is the isoflavonoid compound isolated from Sinkiang licorice root (Glycyrrhiza) .

Glyurallin B	Structural Classification Flavonoids Flavones Leguminosae Glycyrrhiza inflata Batal. Source classification Plants	Others
Glyurallin B is a flavonoid, that can be isolated from licorice (Glycyrrhiza inflata and Glycyrrhiza uralensis). Glyurallin B shows ABTS ⁺ radical scavenging activity and the inhibitory activity on lipid peroxidation, with EC₅₀ values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectivley .

3,4-Didehydroglabridin	Structural Classification Natural Products Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Others
3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury .

Glicoricone	Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones	Monoamine Oxidase Estrogen Receptor/ERR
Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC₅₀ of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity .

Glycycoumarin	Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer	Keap1-Nrf2 AMPK
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

Stearyl glycyrrhetinate	Other Terpenoids Infection Classification of Application Fields Leguminosae Terpenoids Source classification Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Bacterial
Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects .

Glycyrrhizin-6′,6′′-dimethylester	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Umbelliferae	Others
Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .

Glycyrrhizin-6′′-methylester	Structural Classification Glycyrrhiza glabra Linn. Leguminosae Ketones, Aldehydes, Acids Source classification Plants	Others
Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .

Diammonium Glycyrrhizinate	Triterpenes Classification of Application Fields Leguminosae Terpenoids Source classification Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer	Others
Diammonium Glycyrrhizinate, isolated from the licorice root, is a widely used anti-inflammatory agent .

Glycyrrhizin-6'-methylester	Triterpenes Structural Classification Leguminosae Terpenoids Source classification Plants Glycyrrhiza uralensis Fisch.	Others
Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .

Glabrene	Stilbenes Leguminosae Source classification Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch.	Tyrosinase
Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC₅₀ of 3.5 μM .

Licoricone	Infection Flavonoids Monophenols Classification of Application Fields Leguminosae Source classification Phenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones	Bacterial
Licoricone is an flavonoid extracted from licorice, exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains .

Glycyrin	Structural Classification Leguminosae Source classification Coumarins Phenylpropanoids Plants Glycyrrhiza uralensis Fisch.	PPAR Bacterial
Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity .

Isoliquiritin 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Source classification Plants Chalcones Flavonoids Leguminosae Phenols Polyphenols Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	Fungal
Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .

Dibenzoylmethane	Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Keap1-Nrf2
Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2 .

Glabrol	Cardiovascular Disease Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Acyltransferase
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ value of 24.6 μM for rat liver microsomal ACAT activity .

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licorice

Inhibitors & Agonists

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Natural
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