3,4-Didehydroglabridin
3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury.
For research use only. We do not sell to patients.
- CAS No.: 214283-58-6
- Formula: C20H18O4
- Molecular Weight:322.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
3,4-Didehydroglabridin (10 μM) shows protective effects against CCl4 to improve cell viability of the HepG2 from 52.5% to >80%[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 214283-58-6
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Molecular Weight 322.35
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Formula C20H18O4
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SMILES
OC1=CC=C(C2=CC3=C(OC2)C4=C(OC(C)(C)C=C4)C=C3)C(O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kinoshita T, et, al. The isolation and structure elucidation of minor isoflavonoids from licorice of Glycyrrhiza glabra origin. Chem Pharm Bull (Tokyo). 2005 Jul;53(7):847-9. [Content Brief]
[2]. Kuang Y, et, al. Screening of hepatoprotective compounds from licorice against carbon tetrachloride and acetaminophen induced HepG2 cells injury. Phytomedicine. 2017 Oct 15;34:59-66. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)