1. Autophagy
  2. Autophagy
  3. Glycycoumarin

Glycycoumarin 

Cat. No.: HY-N4113
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Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase .

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Glycycoumarin Chemical Structure

Glycycoumarin Chemical Structure

CAS No. : 94805-82-0

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Description

Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase [1] [2].

Molecular Weight

368.38

Formula

C₂₁H₂₀O₆

CAS No.

94805-82-0

SMILES

O=C1C(C2=CC=C(O)C=C2O)=CC3=C(OC)C(C/C=C(C)\C)=C(O)C=C3O1

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Glycycoumarin
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