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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
135 Results for "
linoleic
" in MedChemExpress (MCE) Product Catalog:
Products (135)
135 Results for "linoleic" in MCE Product Catalog:
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DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. DCP-LA activates Ca( 2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. DCP-LA inhibits activation of caspase-3/-9 and protects neurons at least in part from oxidative stress-induced apoptosis .
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AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC50s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC50<4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist .
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3 Cited Publications
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DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca 2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 μM, respectively) . DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis .
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1 Cited Publications
Cat. No.: HY-110406A
CAS No.: 23017-93-8
Synonyms: 13-Hydroperoxylinoleic acid; linoleic acid 13-hydroperoxide
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(±)13-HpODE (13-hydroperoxylinoleic acid) is a racemic mixture of hydroperoxides, which is produced by the oxidation of linoleic acid by lipoxygenase .
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1 Cited Publications
Cat. No.: HY-110406
CAS No.: 33964-75-9
Category:
Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-N10002
CAS No.: 109163-69-1
Category:
Coffea canephora Pierre ex Froehn. Ketones, Aldehydes, Acids Rubiaceae Phenols Polyphenols Plants
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1
1
1 Cited Publications
Cat. No.: HY-W399297
CAS No.: 566-17-6
Synonyms: 7α,12α-Dihydroxycholanoic acid
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Cat. No.: HY-N0729S2
CAS No.: 287111-25-5
Cat. No.: HY-W013812
CAS No.: 544-35-4
Synonyms: linoleic Acid ethyl ester; Mandenol
Cat. No.: HY-W005627
CAS No.: 506-43-4
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(±)9,10-DiHOME is the racemate of 9,10-DiHOME .
Synonyms: 13(S)-HODE
Target:
Synonyms: ω-Alkynyl linoleic acid
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Synonyms: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2
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Research Areas:
9 (Z),11 (E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9 (Z),11 (E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729), and is a conjugated linoleic acid mainly found in meat and dairy products. Conjugated linoleic acid is a bioactive fatty acid that improves body composition, enhances immune system function, and exhibits anti-cancer and anti-atherosclerotic effects .
Cat. No.: HY-W020955
CAS No.: 14243-64-2
Synonyms: Chloro(triphenylphosphine)gold(I)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
