2. Metabolic Enzyme/Protease Apoptosis Others
  3. Endogenous Metabolite Apoptosis Drug Derivative
  4. 9(S)-HODE

9(S)-HODE  (Synonyms: Alpha-dimorphecolic acid)

Cat. No.: HY-113455 Purity: 98%
COA
SDS
Handling Instructions Technical Support

9(S)-HODE (Alpha-dimorphecolic acid) is the major active derivative of Linoleic acid (HY-N0729). 9(S)-HODE regulates the expression of miR-361-3p. 9(S)-HODE reduces cancer cell viability and induces cancer cell apoptosis. 9(S)-HODE can be used in the research of acute myeloid leukemia.

For research use only. We do not sell to patients.

9(S)-HODE

9(S)-HODE Chemical Structure

CAS No. : 73543-67-6

Size Price Stock Quantity
Solvent
100 μg (5.31 mM * 63.5 μL in Ethanol) In-stock

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 9(S)-HODE:

9(S)-HODE Related Antibodies

Top Publications Citing Use of Products

View All Endogenous Metabolite Isoform Specific Products:

View All Isoforms
Human Endogenous Metabolite Microbial Metabolite

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

9(S)-HODE (Alpha-dimorphecolic acid) is the major active derivative of Linoleic acid (HY-N0729). 9(S)-HODE regulates the expression of miR-361-3p. 9(S)-HODE reduces cancer cell viability and induces cancer cell apoptosis. 9(S)-HODE can be used in the research of acute myeloid leukemia[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

9S-HODE (12.5-25 μM; 12-72 h) significantly downregulates the expression of miR-361-3p in HL-60 cells[1].
9S-HODE (25 μM; 0-72 h) inhibits the viability of HL-60 cells and induces apoptosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9(S)-HODE Related Antibodies

Real Time qPCR[1]

Cell Line: human acute myeloid leukemia HL-60 cells
Concentration: 25 μM
Incubation Time: 12, 24, 36, 48, 72 h
Result: Downregulated miR-361-3p expression in a time-dependent manner.
Increased BTG2 mRNA expression.

Apoptosis Analysis[1]

Cell Line: human acute myeloid leukemia HL-60 cells
Concentration: 25 μM
Incubation Time: 48 h
Result: Increased the percentages of early apoptotic (Annexin V+/PI-) and late apoptotic (Annexin V+/PI+) HL-60 cells compared to control.
Molecular Weight

296.44

Formula

C18H32O3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Purity & Documentation

Purity: 98%

SDS (544 KB)

COA (238 KB) MS (1205 KB)

Handling Instructions (2659 KB)
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

9(S)-HODE Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

9(S)-HODE73543-67-6Alpha-dimorphecolic acidEndogenous MetaboliteApoptosisDrug DerivativeDrug derivativecell viabilityEdU-positive cellsmiR-361-3pacute myeloid leukemiacell proliferationBTG2HL-60 cellsapoptosiscancer cellsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
9(S)-HODE
Cat. No.:
HY-113455
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (544 KB) Français - FR (544 KB) Deutsch - DE (544 KB) Norwegian - NO (544 KB) Español - ES (544 KB) Swedish - SV (544 KB) Italian - IT (544 KB) Korean - KR (544 KB) Portuguese - PT (544 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.