9(R)-HODE

(Synonyms: 9(R)-Hydroxyoctadecadienoic acid)

9(R)-HODE is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO).9(R)-HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL.

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  • CAS. Nr.: 10075-11-3
  • Formel: C18H32O3
  • Molecular Weight:296.44
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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