1,2-Dilinoleoyl-sn-glycerol
Based on 1 Customer Validation
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions. 1,2-Dilinoleoyl-sn-glycerol can be prepared from L-dilinoleoylphosphatidylcholine via hydrolysis with phospholipase C.
For research use only. We do not sell to patients.
- Purity : 97.09%
- CAS No.: 24529-89-3
- Formula: C39H68O5
- Molecular Weight:616.95
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
1,2-Dilinoleoyl-sn-glycerol (10 min) is catalyzed for phosphorylation by purified Dictyostelium discoideum DGKA with peak specific activity of ~250 nmol/min/mg at pH 7.0, shows higher activity toward this dipolyunsaturated substrate than toward monounsaturated or mixed saturated/polyunsaturated long-chain diacylglycerols, and has its activity enhanced ~10-fold by phosphatidylserine[2].
1,2-Dilinoleoyl-sn-glycerol levels in pooled human fecal samples decrease with extended storage at -20°C (to 0.27-fold after 1 month), 4°C (to 0.46-fold after 48 h), and room temperature (to 0.50-fold after 48 h) relative to -80°C storage, and its ratio with N-linoleoyl leucine serves as a useful lipidomic stability marker for fecal samples[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 24529-89-3
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Appearance Liquid
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Molecular Weight 616.95
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Formula C39H68O5
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Color Colorless to light yellow
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SMILES
OC[C@@H](COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (261 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Laakso P, et al. Chromatographic resolution of chiral diacylglycerol derivatives: potential in the stereospecific analysis of triacyl-sn-glycerols. Lipids. 1990;25(6):349-353. [Content Brief]
[2]. Ostroski M, et al. Analysis of a novel diacylglycerol kinase from Dictyostelium discoideum: DGKA. Biochemistry. 2005 Aug 2;44(30):10199-207. [Content Brief]
[3]. Sawada H, et al. Investigation of Storage Conditions and Quality Control Markers for Metabolites and Lipids in Human Feces. Metabolites. 2026;16(2):113. Published 2026 Feb 4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,2-Dilinoleoyl-sn-glycerol Related Classifications
HY-117168 Related Classifications
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Keywords
- 1,2-Dilinoleoyl-sn-glycerol
- 24529-89-3
- Endogenous Metabolite
- N-linoleoyl leucine
- phosphatidic acid
- L-dilinoleoylphosphatidylcholine
- Dictyostelium discoideum DGKA
- silica gel HPLC
- long-chain diacylglycerols
- human feces
- phosphatidylserine
- phospholipase C
- (S)-(+)-1-(1-naphthyl)ethyl isocyanate
- Inhibitor
- inhibitor
- inhibit