1,2-Dimyristoyl-sn-glycerol

Cat. No.: HY-128468 Pureza: 99.96%: Ficha de datos
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1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol and a weak second messenger for the activation of PKC.

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1,2-Dimyristoyl-sn-glycerol Estructura química

No. CAS : 60562-16-5

Tamaño	Stock	Cantidad
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
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5 g	Obtener un presupuesto

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PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKC-ι ℩ PKCι

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Descripciòn

1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol and a weak second messenger for the activation of PKC^[1].

Peso molecular

512.81

Fòrmula

C₃₁H₆₀O₅

No. CAS

60562-16-5

Appearance

Solid

Color

White to off-white

SMILES

OC[C@H](OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

Ethanol : 25 mg/mL (48.75 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9500 mL	9.7502 mL	19.5004 mL
5 mM	0.3900 mL	1.9500 mL	3.9001 mL
10 mM	0.1950 mL	0.9750 mL	1.9500 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% EtOH 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (4.88 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.96%

Select Batch:

Ficha de datos (264 KB) SDS (393 KB)

COA (238 KB) HNMR (260 KB) RP-HPLC (202 KB) OR (62 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Sánchez-Piñera P, et al. A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):387-95. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	1.9500 mL	9.7502 mL	19.5004 mL	48.7510 mL
	5 mM	0.3900 mL	1.9500 mL	3.9001 mL	9.7502 mL
	10 mM	0.1950 mL	0.9750 mL	1.9500 mL	4.8751 mL
	15 mM	0.1300 mL	0.6500 mL	1.3000 mL	3.2501 mL
	20 mM	0.0975 mL	0.4875 mL	0.9750 mL	2.4375 mL
	25 mM	0.0780 mL	0.3900 mL	0.7800 mL	1.9500 mL
	30 mM	0.0650 mL	0.3250 mL	0.6500 mL	1.6250 mL
	40 mM	0.0488 mL	0.2438 mL	0.4875 mL	1.2188 mL