1. Anti-infection
    TGF-beta/Smad
    Epigenetics
    Apoptosis
  2. Antibiotic
    PKC
    Apoptosis
  3. Calphostin C

Calphostin C (Synonyms: UCN-1028C)

Cat. No.: HY-105416 Purity: ≥99.0%
Handling Instructions

Calphostin C is a potent and specific inhibitor of protein kinase C. Calphostin C is an antitumor antibiotic. Calphostin C has 1000 times more inhibitory to protein kinase C with an IC50 of 0.05 μM than other protein kinases. Calphostin C induces apoptosis in some tumor cell lines. Calphostin C has potent cytotoxic activity and antitumor activity.

For research use only. We do not sell to patients.

Calphostin C Chemical Structure

Calphostin C Chemical Structure

CAS No. : 121263-19-2

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100 μg USD 1400 In-stock
Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Description

Calphostin C is a potent and specific inhibitor of protein kinase C. Calphostin C is an antitumor antibiotic. Calphostin C has 1000 times more inhibitory to protein kinase C with an IC50 of 0.05 μM than other protein kinases. Calphostin C induces apoptosis in some tumor cell lines. Calphostin C has potent cytotoxic activity and antitumor activity[1].

IC50 & Target

protein kinase C[1]

Molecular Weight

790.76

Formula

C44H38O14

CAS No.
SMILES

O=C(OC(CC1=C(C(C2=C(C=C(C(C3=C4C5=C(O)C=C3OC)=C2C1=C4C(CC(C)OC(C6=CC=CC=C6)=O)=C(OC)C5=O)OC)O)=O)OC)C)OC7=CC=C(C=C7)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: ≥99.0%

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Calphostin C
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