2. GPCR/G Protein
  3. GnRH Receptor
  4. Histrelin acetate

Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Histrelin acetate Chemical Structure

Histrelin acetate Chemical Structure

CAS No. : 220810-26-4

Size Price Stock Quantity
1 mg USD 100 In-stock
5 mg USD 220 In-stock
10 mg USD 350 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Histrelin acetate:

Histrelin acetate Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5].

In Vitro

Histrelin (10-100 nM) acetate stimulates the release of vasopressin (VP) from from isolated rat hypothalamo-neurohypophysial explants[4].
Histrelin (100 nM) acetate stimulates oxytocin (OT) release from the rat hypothalamo-neurohypophysial system[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Histrelin acetate Related Antibodies
In Vivo

Histrelin (0.1 mg/kg, subcutaneous injection) acetate rescues the circulating LH concentrations in Csfmop/Csfmop mice[2].
Histrelin (10,30, or 100 μg /day, subcutaneous injection) acetate reduces the number of endometrial glands and atrophied the stroma in rabbits[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

1323.50 (free base)

Formula

C66H86N18O12.xC2H4O2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Pyr}-His-Trp-Ser-Tyr-{d-His(Bzl)}-Leu-Arg-Pro-{NHEt}
Sequence Shortening

{Pyr}-HWSY-{d-His(Bzl)}-LRP-{NHEt}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Histrelin acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Histrelin220810-26-4GnRH ReceptorGonadotropin releasing hormone receptorGNRHRProstate cancerendometriosisLHvasopressinVPFSHH-N systermInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Histrelin acetate
Cat. No.:
HY-P0056A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.