LGnRH-III, lamprey
Based on 1 Customer Validation
LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 147859-97-0
- Formula: C59H74N18O14
- Molecular Weight:1259.33
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
GnRH[2]
Chemical Information
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CAS No. 147859-97-0
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Appearance Solid
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Molecular Weight 1259.33
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Formula C59H74N18O14
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Color White to off-white
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Sequence
{pGLP}-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2
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Sequence Shortening
{pGLP}-HWSHDWKPG-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (39.70 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (79.41 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98(6):525-34. [Content Brief]
[2]. Manea M, et al. lGnRH-III -- a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20(4):439-49. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.7941 mL | 3.9704 mL | 7.9407 mL | 19.8518 mL |
| 5 mM | 0.1588 mL | 0.7941 mL | 1.5881 mL | 3.9704 mL | |
| 10 mM | 0.0794 mL | 0.3970 mL | 0.7941 mL | 1.9852 mL | |
| 15 mM | 0.0529 mL | 0.2647 mL | 0.5294 mL | 1.3235 mL | |
| 20 mM | 0.0397 mL | 0.1985 mL | 0.3970 mL | 0.9926 mL | |
| 25 mM | 0.0318 mL | 0.1588 mL | 0.3176 mL | 0.7941 mL | |
| 30 mM | 0.0265 mL | 0.1323 mL | 0.2647 mL | 0.6617 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.