147859-97-0
Chemical Structure
LGnRH-III, lamprey
- CAS No.: 147859-97-0
- Formula:C59H74N18O14
- Molecular Weight:1259.33
IUPAC Name: (3S,6S,9S,12S,15S)-3,12-bis((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-15-(((S)-1-(((S)-6-amino-1-((S)-2-((2-amino-2-oxoethyl)carbamoyl)pyrrolidin-1-yl)-1-oxohexan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamoyl)-9-(hydroxymethyl)-1,4,7,
InChIKey: RTASYRSYWSLWJV-CSYZDTNESA-N
SMILES: O=C(N1[C@@H](CCC1)C(NCC(N)=O)=O)[C@H](CCCCN)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@@H]2CCC(N2)=O)=O)CC3=CN=CN3)=O)CC4=CNC5=CC=CC=C45)=O)=O)CC6=CN=CN6)=O)=O)CC7=CNC8=CC=CC=C78)=O
Biological Activity: LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LGnRH-III, lamprey | 99.80% | LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities. | ||||||||||||||||||||
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- [1]. Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98(6):525-34. [Content Brief]
- [2]. Manea M, et al. lGnRH-III -- a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20(4):439-49. [Content Brief]
Keywords
