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vitamin-b6

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37

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7

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1744
    Pyridoxal phosphate
    4 Publications Verification

    Pyridoxal 5′-phosphate; Pyridoxyl phosphate

    Reverse Transcriptase Endogenous Metabolite ERK Amyloid-β Neurological Disease Metabolic Disease Cancer
    Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
    Pyridoxal phosphate
  • HY-B1328
    Pyridoxine
    Maximum Cited Publications
    7 Publications Verification

    Pyridoxol

    Environmental Pollutants Endogenous Metabolite Keap1-Nrf2 Neurological Disease Cancer
    Pyridoxine (Pyridoxol) is one of the components of vitamin B6. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine
  • HY-N0682
    Pyridoxine hydrochloride
    Maximum Cited Publications
    7 Publications Verification

    vitamin b6 hydrochloride

    Environmental Pollutants Endogenous Metabolite Keap1-Nrf2 Neurological Disease Cancer
    Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine hydrochloride
  • HY-W011727A
    Pyridoxal 5'-​phosphate monohydrate
    4 Publications Verification

    Pyridoxal phosphate monohydrate

    Endogenous Metabolite Amyloid-β ERK Neurological Disease Metabolic Disease Cancer
    Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .
    Pyridoxal 5'-​phosphate monohydrate
  • HY-N0682S3

    Pyridoxol-13C4 hydrochloride; vitamin b6-13C4 hydrochloride

    Isotope-Labeled Compounds Endogenous Metabolite Keap1-Nrf2 Neurological Disease
    Pyridoxine- 13C4 (hydrochloride) is the 13C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine-13C4 hydrochloride
  • HY-W027446
    Pyridoxal hydrochloride
    1 Publications Verification

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS) .
    Pyridoxal hydrochloride
  • HY-W011727S

    Pyridoxal 5'-phosphate-d3

    Endogenous Metabolite Amyloid-β ERK Neurological Disease Metabolic Disease Cancer
    Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
    Pyridoxal Phosphate-d3
  • HY-B0910A
    Pyrithioxin dihydrochloride
    2 Publications Verification

    Pyritinol dihydrochloride; Pyridoxine disulfide dihydrochloride; vitamin b6 disulfide dihydrochloride

    Drug Derivative Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Pyrithioxin (Pyritinol) dihydrochloride is the dihydrochloride salt of Pyrithioxin (HY-B0910). Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis [6] .
    Pyrithioxin dihydrochloride
  • HY-W011727
    Pyridoxal 5'-phosphate hydrate
    4 Publications Verification

    Pyridoxal phosphate hydrate

    Endogenous Metabolite Amyloid-β ERK Neurological Disease Metabolic Disease Cancer
    Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
    Pyridoxal 5'-phosphate hydrate
  • HY-113493

    Endogenous Metabolite Metabolic Disease
    4-Pyridoxic acid is an endogenous substrate of renal organic anion transporters (OAT1/3) and a catabolite of vitamin B6. 4-Pyridoxic acid is excreted through OAT1/3-mediated tubular active secretion, which can reflect OAT1/3 activity. Elevated plasma concentrations of 4-Pyridoxic acid are associated with decreased OAT1/3 activity in chronic kidney disease (CKD) and can be used as a biomarker to reflect the severity of knee osteoarthritis (KOA) and lumbar spondylosis (LS) .
    4-Pyridoxic acid
  • HY-116073

    Acyltransferase Infection Cancer
    L-Penicillamine is an orally active serine palmitoyltransferase (SPT) inhibitor. L-Penicillamine inactivates the PLP cofactor by forming adducts, thereby inhibiting SPT activity and reducing sphingolipid biosynthesis. L-Penicillamine not only blocks tumor access to vitamin B6, but also stabilizes the human papillomavirus 16 E6 oncoprotein monomer and inhibits its polymerization, exhibiting a unique anticancer mechanism. L-Penicillamine effectively delays the growth of Sarcoma-180, induces tumor necrosis and prolongs survival (though long-term use may lead to Pyridoxine (HY-B1328) deficiency and weight loss) .
    L-Penicillamine
  • HY-B1746

    Endogenous Metabolite Neurological Disease
    Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of Pyridoxal 5'-?phosphate monohydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .
    Pyridoxamine 5′-phosphate
  • HY-Y0032
    Thiosemicarbazide
    1 Publications Verification

    Orthopoxvirus Infection Others Cancer
    Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
    Thiosemicarbazide
  • HY-N0682S1

    Pyridoxol-d2 hydrochloride; vitamin b6-d2 hydrochloride

    Isotope-Labeled Compounds Endogenous Metabolite Keap1-Nrf2 Neurological Disease
    Pyridoxine-d2 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine-d2 hydrochloride
  • HY-B1744R

    Pyridoxal 5′-phosphate (Standard); Pyridoxyl phosphate (Standard)

    Reference Standards Reverse Transcriptase Endogenous Metabolite Neurological Disease
    Pyridoxal phosphate (Standard) is the analytical standard of Pyridoxal phosphate. This product is intended for research and analytical applications. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
    Pyridoxal phosphate (Standard)
  • HY-107469
    Pyridoxal
    1 Publications Verification

    Pyridoxaldehyde

    Endogenous Metabolite Neurological Disease Metabolic Disease
    Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS) .
    Pyridoxal
  • HY-N0682S

    Pyridoxol-d3 hydrochloride; vitamin b6-d3 hydrochloride

    Endogenous Metabolite Keap1-Nrf2 Neurological Disease
    Pyridoxine-d3 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine-d3 hydrochloride
  • HY-113493S1

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine .
    4-Pyridoxic acid-d3
  • HY-N0682R

    vitamin b6 hydrochloride (Standard)

    Reference Standards Endogenous Metabolite Keap1-Nrf2 Neurological Disease Cancer
    Pyridoxine (hydrochloride) (Standard) is the analytical standard of Pyridoxine (hydrochloride). This product is intended for research and analytical applications. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine hydrochloride (Standard)
  • HY-107469R
    Pyridoxal (Standard)
    1 Publications Verification

    Pyridoxaldehyde (Standard)

    Endogenous Metabolite Reference Standards Neurological Disease Metabolic Disease
    Pyridoxal (Standard) is the analytical standard of Pyridoxal. This product is intended for research and analytical applications. Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS)[1][2][3].
    Pyridoxal (Standard)
  • HY-B0910
    Pyrithioxin
    2 Publications Verification

    Pyritinol; Pyridoxine disulfide; vitamin b6 disulfide

    Drug Derivative Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis [6] .
    Pyrithioxin
  • HY-B1744S

    Isotope-Labeled Compounds Reverse Transcriptase Endogenous Metabolite Neurological Disease
    Pyridoxal phosphate-d5 is the deuterium labeled Pyridoxal phosphate. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia .
    Pyridoxal phosphate-d5
  • HY-113493R

    Reference Standards Endogenous Metabolite Metabolic Disease
    4-Pyridoxic acid (Standard) is the analytical standard of 4-Pyridoxic acid. This product is intended for research and analytical applications. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine.
    4-Pyridoxic acid (Standard)
  • HY-177828

    Liposome Metabolic Disease
    Liposomal Vitamin B6 is a specialized delivery system that encapsulates vitamin B6 within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin B6. Vitamin B6 (Thiamin) is a cofactor required for
    Liposomal Vitamin B6
  • HY-W747907

    β-Pyracin

    Endogenous Metabolite Others
    4-Pyridoxolactone (β-Pyracin) is a critical substrate in vitamin B6 degradation pathway I, primarily involved in the vitamin B6 metabolic process mediated by soil microorganisms. 4-Pyridoxolactone serves as the specific substrate for 4-pyridoxolactonase, undergoing a zinc-dependent lactone-ring hydrolysis reaction catalyzed by this enzyme to generate 4-pyridoxic acid (4PA) .
    4-Pyridoxolactone
  • HY-W717654

    Endogenous Metabolite Metabolic Disease
    1-Deoxy-D-xylulose 5-phosphate (DXP) is a biosynthetic precursor to isoprenoids, thiamin (vitamin B1), and pyridoxol (vitamin B6). 1-Deoxy-D-xylulose 5-phosphate can be utilized in metabolic research .
    1-Deoxy-D-xylulose 5-phosphate
  • HY-Y0032R

    Orthopoxvirus Reference Standards Infection Others Cancer
    Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
    Thiosemicarbazide (Standard)
  • HY-N0682S2

    Pyridoxol-d5 hydrochloride; vitamin b6-d5 hydrochloride

    Keap1-Nrf2 Endogenous Metabolite Neurological Disease
    Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride . Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway .
    Pyridoxine-d5 hydrochloride
  • HY-113601

    Bacterial Others
    Linatine is an antagonist for Vitamin B6 (HY-150525). Linatine inhibits the growth of chicken and Azotobacter vinelandii, induces vitamin B6 deficiency symptoms in chickens .
    Linatine
  • HY-B0910AR

    Pyritinol dihydrochloride (Standard); Pyridoxine disulfide dihydrochloride (Standard); vitamin b6 disulfide dihydrochloride (Standard)

    Reference Standards Drug Derivative Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Pyrithioxin (Pyritinol) dihydrochloride (Standard) is the analytical standard of Pyrithioxin dihydrochloride (HY-B0910A). Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis [6] .
    Pyrithioxin dihydrochloride (Standard)
  • HY-W011727AR

    Pyridoxal phosphate monohydrate (Standard)

    Reference Standards Endogenous Metabolite Amyloid-β ERK Neurological Disease Metabolic Disease Cancer
    Pyridoxal 5'-​phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-​phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
    Pyridoxal 5'-?phosphate monohydrate (Standard)
  • HY-176959

    Drug Intermediate Others
    1-Amino-3-(phosphonooxy)-2-propanone is a drug intermediate that can be used for the synthesis of vitamin B6 .
    1-Amino-3-(phosphonooxy)-2-propanone
  • HY-164825

    Endogenous Metabolite Others
    Pyridoxine tri(2-hexyldecanoate) is a derivative of Vitamin B6 (HY-150525). Pyridoxine tri(2-hexyldecanoate) is a cosmetic ingredient .
    Pyridoxine tri(2-hexyldecanoate)
  • HY-E70999

    Endogenous Metabolite Metabolic Disease
    L-Histidine Decarboxylase, Lactobacillus 30a (EC 4.1.1.22) catalyzes the conversion of histidine to histamine with the help of vitamin B6. The specific reaction is as follows: Histidine decarboxylase catalyzes the conversion of histidine to histamine.
    L-Histidine Decarboxylase, Lactobacillus 30a
  • HY-W011727R

    Pyridoxal phosphate hydrate (Standard)

    Endogenous Metabolite Reference Standards Amyloid-β ERK Neurological Disease Metabolic Disease Cancer
    Pyridoxal 5'-phosphate (hydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (hydrate) (HY-W011727). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
    Pyridoxal 5'-phosphate hydrate (Standard)
  • HY-W027446R

    Reference Standards Endogenous Metabolite Neurological Disease Metabolic Disease
    Pyridoxal hydrochloride (Standard) is the analytical standard of Pyridoxal hydrochloride. This product is intended for research and analytical applications. Pyridoxal hydrochloride, the hydrochloride form of Pyridoxal (HY-107469), is a newly developed neuroprotective agent. Pyridoxal hydrochloride is one of the major forms of vitamin B6. Pyridoxal hydrochloride is solvolyzed in methanol to form pyridoxal monomethylacetal. Pyridoxal is phosphorylated by pyridoxal kinase to Pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-Pyridoxic acid (HY-113493) which is excreted in the urine. Pyridoxal hydrochloride is proming for research of carpal tunnel syndrome (CTS) .
    Pyridoxal hydrochloride (Standard)
  • HY-124655

    LPL Receptor Inflammation/Immunology
    S1PL-IN-2 (Compound 28) is a potent sphingosine-1-phosphate lyase (S1PL) inhibitor with an IC50 of 120 nM. S1PL-IN-2 shows an IC50 of 230 nM on HEK293 cells. S1PL-IN-2 block the conversion of Vitamin B6 into the active pyridoxal-4-phosphate cofactor required for S1P lyase activity. S1PL-IN-2 can be used for the researches of inflammation and immunology, such as rheumatoid arthritis .
    S1PL-IN-
2

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