Pyridoxal 5'-phosphate hydrate (Standard)
Pyridoxal 5'-phosphate (hydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (hydrate) (HY-W011727). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 853645-22-4
- Formula: C8H10NO6P
- Molecular Weight:247.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 853645-22-4
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Molecular Weight 247.14
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Formula C8H10NO6P
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SMILES
O=CC1=C(O)C(C)=NC=C1COP(O)(O)=O.[x H2O]
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Synonyms
Pyridoxal phosphate hydrate (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Allen GF, et al. Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.J Neurochem. 2010 Jul;114(1):87-96. [Content Brief]
[2]. Calderón-Ospina CA, et al. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.CNS Neurosci Ther. 2020 Jan;26(1):5-13. [Content Brief]
[3]. Zhang P, et al., High concentrations of pyridoxal stimulate the expression of IGFBP1 in HepG2 cells through upregulation of the ERK/c‑Jun pathway. Mol Med Rep. 2013 Oct;8(4):973-8. [Content Brief]
[4]. Choi JM, et al., Membrane-Free Stem Cells and Pyridoxal 5'-Phosphate Synergistically Enhance Cognitive Function in Alzheimer's Disease Mouse Model. Antioxidants (Basel). 2022 Mar 21;11(3):601. [Content Brief]
[5]. Zhang L, et al., Pyridoxine 5'-phosphate oxidase is a novel therapeutic target and regulated by the TGF-β signalling pathway in epithelial ovarian cancer. Cell Death Dis. 2017 Dec 13;8(12):3214. [Content Brief]
[6]. Nakamura S, et al., Pyridoxal phosphate prevents progression of diabetic nephropathy. Nephrol Dial Transplant. 2007 Aug;22(8):2165-74. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pyridoxal 5'-phosphate hydrate (Standard) Related Classifications
HY-W011727R Related Classifications
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