1. Neuronal Signaling
  2. Monoamine Oxidase
  3. β-Aminopropionitrile

β-Aminopropionitrile 

Cat. No.: HY-Y1750 Purity: 99.99%
Handling Instructions

β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes.

For research use only. We do not sell to patients.

β-Aminopropionitrile Chemical Structure

β-Aminopropionitrile Chemical Structure

CAS No. : 151-18-8

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 61 In-stock
Estimated Time of Arrival: December 31
500 mg USD 55 In-stock
Estimated Time of Arrival: December 31
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Description

β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

β-Aminopropionitrile blocks the hypoxia-induced EMT morphological and marker protein changes, and inhibited invasion and migration capacities of cervical carcinoma cells in vitro[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

70.09

Formula

C₃H₆N₂

CAS No.

151-18-8

SMILES

N#CCCN

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 130 mg/mL (1854.76 mM; Need ultrasonic)

H2O : 50 mg/mL (713.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 14.2674 mL 71.3369 mL 142.6737 mL
5 mM 2.8535 mL 14.2674 mL 28.5347 mL
10 mM 1.4267 mL 7.1337 mL 14.2674 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.25 mg/mL (46.37 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.25 mg/mL (46.37 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.25 mg/mL (46.37 mM); Clear solution

  • 4.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (1426.74 mM); Clear solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References

Purity: 99.99%

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Keywords:

β-AminopropionitrileMonoamine OxidaseMAOinvasionmigrationcapacitiescervicacarcinomacellsepithelial-mesenchymaltransitionmetastasisInhibitorinhibitorinhibit

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Product Name:
β-Aminopropionitrile
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HY-Y1750
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