2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2472
    Medicagenic acid 599-07-5 98.97%
    Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes. Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE.
    Medicagenic acid
  • HY-N2512
    1-Monomyristin 589-68-4 98.0%
    1-Monomyristin acts as an insecticide, enzyme inhibitor, antibacterial and antifungal agent, with an IC50 of 18 μM against rat FAAH and an IC50 of 32 μM against rat MAGL. 1-Monomyristin inhibits 2-oleoylglycerol hydrolysis via MAGL. 1-Monomyristin suppresses the growth of Staphylococcus aureus, Aggregatibacter actinomycetemcomitans and Candida albicans. 1-Monomyristin is lethal to brine shrimp. 1-Monomyristin exhibits marginal cytotoxicity against prostate cancer cells. 1-Monomyristin is applicable to research related to bacterial infections, fungal infections, renal cancer, prostate adenocarcinoma and pancreatic cancer.
    1-Monomyristin
  • HY-N2590
    Lupenone 1617-70-5 ≥98.0%
    Lupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, antiviral, antidiabetic and anticancer activities.
    Lupenone
  • HY-N2612
    O-Methyldauricine 2202-17-7
    O-Methyldauricine ((-)-O-Methyldauricine) is an alkaloid with benzylisoquinoline group, which can be separated from P. ophthalmicus. O-Methyldauricine has antibacterial activity.
    O-Methyldauricine
  • HY-N3239
    Mulberrofuran G 87085-00-5
    Mulberrofuran G is a NOX inhibitor (IC50: 6.9 μM) and tyrosinase inhibitor. Mulberrofuran G exhibits anti-inflammatory, antioxidant, antiviral, antitumor, and neuroprotective effects. Mulberrofuran G can be used in the research of tumors, nervous system diseases, and other conditions.
    Mulberrofuran G
  • HY-N3557
    Cauloside A 17184-21-3 99.75%
    Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity.
    Cauloside A
  • HY-N3990
    Hardwickiic acid 1782-65-6 ≥98.0%
    Hardwickiic acid ((-)-Hardwickiic acid) is a diterpenoid compound. Hardwickiic acid can block tetrodotoxin-sensitive voltage-dependent sodium channels and possesses multiple activities such as insecticidal, antinociceptive, and neurotransmitter release-regulating effects. Hardwickiic acid can be used in the study of neurological diseases.
    Hardwickiic acid
  • HY-N4116
    Xanthyletin 553-19-5 98.87%
    Xanthyletin is a coumarin isolated from Stauranthus perforatus, with anti-tumor and anti-bacterial activities. Xanthyletin also inhibits symbiotic fungus cultivated by leaf-cutting ants.
    Xanthyletin
  • HY-N4168
    3-O-Caffeoylquinic acid methyl ester 123483-19-2 99.64%
    3-O-Caffeoylquinic acid methyl ester is a monocaffeoylquinic acid derivative and phenolic acid component, which can be found in the whole plant of Pyrrosia calvata (Backer) Ching and the flower buds of Lonicera japonica Thunb.
    3-O-Caffeoylquinic acid methyl ester
  • HY-N6015
    Bacopasaponin C 178064-13-6 99.76%
    Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC50 of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani.
    Bacopasaponin C
  • HY-N6717
    Tentoxin 28540-82-1 ≥99.0%
    Tentoxin is a cyclic tetrapeptide isolated from Alternaria tenuis, acts as a herbicide, causes seedling chlorosis, inhibits cyclic photophosphorylation and functions as an energy transfer inhibitor.
    Tentoxin
  • HY-N6738
    Bafilomycin B1 88899-56-3 98.10%
    Bafilomycin B1 is a macrolide antibiotic that can be isolated from mycelium of Streptomyces gresuis. Bafilomycin B1 is neuroprotective against Chloroquine (HY-17589A)-induced death. Bafilomycin B1 is a structural analog of Bafilomycin A1 and has the ability to inhibit V-ATPase. Bafilomycin B1 inhibits significantly the oxidized low density lipoprotein (LDL)-induced accumulation of lipid droplets.
    Bafilomycin B1
  • HY-N6741
    β-Zearalenol 71030-11-0 99.84%
    β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level.
    β-Zearalenol
  • HY-N6781
    Ophiobolin A 4611-05-6 98.86%
    Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase, with an IC50 value of 9 μM. Ophiobolin A antimicrobial and anticancer activity.
    Ophiobolin A
  • HY-N6935
    Sennidin B 517-44-2 99.25%
    Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .
    Sennidin B
  • HY-N7012
    7,3',4'-Tri-O-methylluteolin 29080-58-8 99.28%
    7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3',4'-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. 7,3',4'-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3',4'-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3',4'-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activitiessup>[4]sup>[5].
    7,3',4'-Tri-O-methylluteolin
  • HY-N7060
    Helicin 618-65-5 99.95%
    Helicin, found in Rosaceae, is a moderate syrB inducer. Helicon can be hydrolyzed by BglY enzyme.
    Helicin
  • HY-N7141
    Spiramycin I 24916-50-5
    Spiramycin I is a macrolide antibiotic and antiparasitic.
    Spiramycin I
  • HY-N7227
    Anonaine 1862-41-5
    Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor.
    Anonaine
  • HY-N7252
    Daphnin 486-55-5 99.85%
    Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever.
    Daphnin
Cat. No. Product Name / Synonyms Application Reactivity