1. Anti-infection
    PI3K/Akt/mTOR
    Membrane Transporter/Ion Channel
  2. HCV
    Akt
    GLUT
  3. Sennidin B

Sennidin B 

Cat. No.: HY-N6935
Handling Instructions

Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

For research use only. We do not sell to patients.

Sennidin B Chemical Structure

Sennidin B Chemical Structure

CAS No. : 517-44-2

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Description

Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation [1][2].

IC50 & Target

GLUT4

 

Akt

 

HCV NS3

 

Molecular Weight

538.46

Formula

C₃₀H₁₈O₁₀

CAS No.

517-44-2

SMILES

O=C1C2=C(O)C=C(C(O)=O)C=C2[[email protected]@]([[email protected]]3([H])C4=CC(C(O)=O)=CC(O)=C4C(C5=C(O)C=CC=C35)=O)([H])C6=CC=CC(O)=C16

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Sennidin BHCVAktGLUTHepatitis C virusPKBProtein kinase BGlucose transporterInhibitorinhibitorinhibit

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