Cassia angustifolia

Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis.

Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC₅₀: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases.

Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC₅₀ of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).

Sennoside B (Standard) is the analytical standard of Sennoside B. This product is intended for research and analytical applications. Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia). Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway.

Sennoside D (Standard) is the analytical standard of Sennoside D. This product is intended for research and analytical applications. Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).

Sennoside C (Standard) is the analytical standard of Sennoside C (HY-N1972). This product is intended for research and analytical applications. Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC₅₀: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases.

Sennidin B (Standard) is the analytical standard of Sennidin B. This product is intended for research and analytical applications. Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .