1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100997
    Chloroorienticin A
    99.81%
    Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci.
    Chloroorienticin A
  • HY-N14958
    Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV
    Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV is an antibiotic, and its biological activity is similar to that of Tylosin (HY-B0519A).
    Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV
  • HY-N12228
    Phenelfamycin E
    Phenelfamycin E is an elfamycin-type antibiotic and is active against Gram-positive anaerobes, including Clostridium difficile. Phenelfamycin E can be used for anti-bacteria research.
    Phenelfamycin E
  • HY-B1327S
    Chlortetracycline-d6 hydrochloride
    Chlortetracycline-d6 (hydrochloride) is the deuterium labeled Chlortetracycline hydrochloride. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline-d<sub>6</sub> hydrochloride
  • HY-125723
    Echinocandin B
    Echinocandin B (SL 7810) is a lipopeptide antifungal antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits β-1,3-glucan activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species.
    Echinocandin B
  • HY-B0242S1
    Sulfanilamide-d4
    99.99%
    Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
    Sulfanilamide-d<sub>4</sub>
  • HY-129325
    Cytochalasin H
    Cytochalasin H is a nature product that could be isolated from fungus Phomopsis sp. Cytochalasin H inhibits cell growth and induces apoptosis. Cytochalasin H has anti-angiogenic activity. Cytochalasin H is an antibiotic and has antibacterial activity.
    Cytochalasin H
  • HY-101021
    Ascochlorin
    Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, mediates its anti-tumor effects predominantly through the suppression of STAT3 signaling cascade. Ascochlorin induces apoptosis. Anti-inflammatory activity.
    Ascochlorin
  • HY-17425AS
    Valacyclovir-d8 hydrochloride
    98.0%
    Valacyclovir-d8 (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) .
    Valacyclovir-d<sub>8</sub> hydrochloride
  • HY-14989R
    SQ109 (Standard)
    SQ109 (Standard) is the analytical standard of SQ109. This product is intended for research and analytical applications. SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent.
    SQ109 (Standard)
  • HY-P11021A
    ToAP2 TFA
    ToAP2 TFA is a potent antimicrobial peptide. ToAP2 TFA affects C. albicans membrane permeability and produces changes in fungal cell morphology.
    ToAP2 TFA
  • HY-124210
    Formycin B
    Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia.
    Formycin B
  • HY-124035
    Streptochlorin
    Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1.
    Streptochlorin
  • HY-124439
    Setomimycin
    Setomimycin is a potent antibiotic. Setomimycin inhibits the SARS-CoV-2 Mpro enzyme with an IC50 value of 12.02 µM. Setomimycin shows anti-inflammatory and antioxidant properties. Setomimycin shows antiproliferative and antitumor activity.
    Setomimycin
  • HY-B1526R
    Thiacetazone (Standard)
    Thiacetazone (Standard) is the analytical standard of Thiacetazone. This product is intended for research and analytical applications. Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL[1].
    Thiacetazone (Standard)
  • HY-N6800
    Netropsin
    Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity.
    Netropsin
  • HY-N20645
    Capricostatin A
    Capricostatin A is a glycosylated heteromeric depsipeptide and Antibacterial agent. Capricostatin A is present in the fungus Austroacremonium gemini MST-FP2131. Capricostatin A inhibits the growth of Gram-positive bacteria, including Bacillus subtilis, Staphylococcus aureus, and MRSA. Capricostatin A exhibits no antifungal activity against Saccharomyces cerevisiae and no cytotoxicity against mammalian cells. Capricostatin A can be used in the research of bacterial infections caused by Bacillus subtilis and Staphylococcus aureus.
    Capricostatin A
  • HY-P2170
    XMP-629
    XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand.
    XMP-629
  • HY-B0308S
    Sparfloxacin-d5
    Sparfloxacin-d5 is deuterium labeled Sparfloxacin (HY-B0308). Sparfloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
    Sparfloxacin-d<sub>5</sub>
  • HY-125721
    Tetranactin
    Tetranactin is an orally active antibiotic that has insecticidal properties and can inhibit the growth of Gram-positive bacteria and plant pathogenic fungal in vitro. Tetranactin LD50 for intraperitoneal injection in mice is greater than 300 mg/kg, and the LD50 is greater than 15,000 mg/kg.
    Tetranactin

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