2. Anti-infection
  3. Beta-lactamase Bacterial Antibiotic
  4. Clavulanate potassium

Clavulanate (potassium)  (Synonyms: クラブラン酸カリウム)

製品番号: HY-A0256A 純度: 99.86%
COA 取扱説明書 Technical Support

Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 61177-45-5

容量 価格（税別） 在庫状況 数量
5 mg $70 在庫あり
10 mg $122 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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カスタマーレビュー

Based on 8 publication(s) in Google Scholar

Other Forms of Clavulanate potassium:

Clavulanate (potassium) 関連抗体

Top Publications Citing Use of Products

    Clavulanate potassium purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2024 Dec 5:984:177017.  [Abstract]

    Clavulanic acid (CLAV, 10 mg/kg, injected twice daily for 7 days) did not change GLT-1 mRNA expression in the rat PFC.

    Clavulanate potassium purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2024 Dec 5:984:177017.  [Abstract]

    Clavulanic acid (CLAV, 10 mg/kg, injected twice daily for 7 days) increased expression of GLT-1 protein in the rat PFC.

    Clavulanate potassium purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2023 Oct 27;24(21):15657.

    Average body weight at baseline and after treatment, by group. Two‑way ANOVA showed no significant differences between groups. n = 8–9 per group. Color dots represent individual data. CA (clavulanic acid, 5 mg/kg, i.p. for 7 days); DHK (dihydrokainic acid).

    Clavulanate potassium purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2023 Oct 27;24(21):15657.

    Post hoc comparisons using Tukey’s test indicated the total time spent in closed arms to be higher in the Khat and Khat‑CA‑DHK (CA: clavulanic acid, 5 mg/kg, i.p. for 7 days) groups as compared with the Control and Khat‑CA groups.

    Clavulanate potassium purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2023 Oct 27;24(21):15657.

    Clavulanic acid (5 mg/kg, i.p. for 7 days) reversed the Khat‑induced decrease in GLT‑1 and xCT expression in mice.

    Beta-lactamase アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Metallo-β-lactamase (MBL) Serine β-lactamase (SBL)

    Antibiotic アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

    • 生物活性

    • 純度とドキュメンテーション

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    製品説明

    Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].

    IC50 & Target

    β-lactam

     

    体外実験

    Clavulanate potassium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].
    Clavulanate potassium (0.25 mg/L, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Clavulanate (potassium) 関連抗体
    分子量

    237.25

    分子式

    C8H8KNO5
    CAS 番号
    Appearance

    Solid

    Color

    Light yellow to brown

    SMILES

    O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O[K]
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
    純度とドキュメンテーション

    純度: 99.86%

    COA (250 KB) HNMR (214 KB) RP-HPLC (262 KB) MS (71 KB)

    取扱説明書 (2659 KB)
    参考文献
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    Clavulanate potassium Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Clavulanate61177-45-5Beta-lactamaseBacterialAntibioticβ-lactamaseAmoxycillinbeta-lactamasebeta-lactambacterialInhibitorinhibitorinhibit

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    製品名:
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    製品番号:
    HY-A0256A
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