1. Anti-infection
  2. Beta-lactamase Bacterial Antibiotic
  3. Potassium clavulanate cellulose

Potassium clavulanate cellulose  (Synonyms: Potassium clavulanate:cellulose (1:1))

Cat. No.: HY-19964
COA Handling Instructions

Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Clavulanate potassium is a form of Clavulanic acid. Clavulanate potassium fights bacteria that resistant to penicillins and other antibiotics. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.

For research use only. We do not sell to patients.

Potassium clavulanate cellulose Chemical Structure

Potassium clavulanate cellulose Chemical Structure

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Potassium clavulanate cellulose:

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Description

Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Clavulanate potassium is a form of Clavulanic acid. Clavulanate potassium fights bacteria that resistant to penicillins and other antibiotics. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin[1][2].

IC50 & Target

β-lactam

 

In Vitro

Clavulanate potassium (2 μg/mL) is susceptive to β-lactamase-positive and β-lactamase-negative Bacteroides spp. and Fusobacterium spp. with the combination of amoxicillin (4 μg/mL) and ticarcillin (64 μg/mL)[1].
Clavulanate potassium (16 μg/mL) inhibits B. intermedius, B. bivius, B. disiens, B. oris, B. buccae, B. buccalis and B. loeschei with MIC50 values of 8 μg/mL[1].
Clavulanate potassium (16 μg/mL) inhibits B. melaninogenicus, B. oralis and F. varium with MIC50 values of 16 μg/mL[1].
Clavulanate potassium (2 μg/mL) raises amoxicillin susceptibility rates for β-lactamase-positive Bacteroides species and fusobacteria from 41.3 to 90.8% and from 64.2 to 88.7%, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Clavulanate potassium (125 mg; 20 d) protects 75% of mice with experimental pneumonitis compared with no survivors in the control group[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

238.26 (Potassiumclavulanate)

Formula

C8H9NO5K .(C6H10O5)n

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](C)[C@@H](CO)O2)[C@@H](CO)O[C@@H](OC)[C@@H]1O.O=C([C@@H](/C(O[C@]3([H])C4)=C/CO)N3C4=O)O[K].[n]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

H2O : < 0.1 mg/mL (insoluble)

Purity & Documentation
References
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Potassium clavulanate cellulose Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Potassium clavulanate cellulose
Cat. No.:
HY-19964
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