Potassium clavulanate cellulose
Based on 2 publication(s) in Google Scholar
Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Clavulanate potassium is a form of Clavulanic acid. Clavulanate potassium fights bacteria that resistant to penicillins and other antibiotics. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C8H9NO5K .(C6H10O5)n
- Molecular Weight:238.26 (Potassiumclavulanate)
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Potassium clavulanate cellulose
MoreAll Beta-lactamase Isoforms
MoreAll Antibiotic Isoforms
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Biological Activity
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β-lactam |
Clavulanate potassium (2 μg/mL) is susceptive to β-lactamase-positive and β-lactamase-negative Bacteroides spp. and Fusobacterium spp. with the combination of amoxicillin (4 μg/mL) and ticarcillin (64 μg/mL)[1]. Clavulanate potassium (16 μg/mL) inhibits B. intermedius, B. bivius, B. disiens, B. oris, B. buccae, B. buccalis and B. loeschei with MIC50 values of 8 μg/mL[1]. Clavulanate potassium (16 μg/mL) inhibits B. melaninogenicus, B. oralis and F. varium with MIC50 values of 16 μg/mL[1]. Clavulanate potassium (2 μg/mL) raises amoxicillin susceptibility rates for β-lactamase-positive Bacteroides species and fusobacteria from 41.3 to 90.8% and from 64.2 to 88.7%, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 238.26 (Potassiumclavulanate)
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Formula C8H9NO5K .(C6H10O5)n
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Color White to off-white
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SMILES
O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](C)[C@@H](CO)O2)[C@@H](CO)O[C@@H](OC)[C@@H]1O.O=C([C@@H](/C(O[C@]3([H])C4)=C/CO)N3C4=O)O[K].[n]
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Synonyms
Potassium clavulanate:cellulose (1:1)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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J Pharmacol Toxicol Methods
2019 Jan-Feb:95:79-85. PMID: 30529169 -
Behav Neurosci
The effects of clavulanic acid and amoxicillin on cue-primed reinstatement of cocaine seeking. [Abstract]2019 Apr;133(2):247-254. PMID: 30714803
Solvent & Solubility
DMSO : < 1 mg/mL (insoluble or slightly soluble)
H2O : < 0.1 mg/mL (insoluble)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Appelbaum PC, et al. Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers. Antimicrob Agents Chemother. 1990 Aug;34(8):1546-50. [Content Brief]
[2]. Beale AS, et al. Comparative activities of amoxycillin, amoxycillin/clavulanic acid and tetracycline against Chlamydia trachomatis in cell culture and in an experimental mouse pneumonitis. J Antimicrob Chemother. 1991 May;27(5):627-38. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Potassium clavulanate cellulose Related Classifications
HY-19964 Related Classifications
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