Search Result
Results for "
dihydro-
" in MedChemExpress (MCE) Product Catalog:
8
Biochemical Assay Reagents
19
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N6787
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dihydrothymine
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Endogenous Metabolite
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Metabolic Disease
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5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels .
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- HY-131252
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dihydro E2020
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Cholinesterase (ChE)
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Neurological Disease
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Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively .
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- HY-N10497
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nAChR
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Neurological Disease
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Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced .
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- HY-146770S
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- HY-146775S
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- HY-106689
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- HY-106689A
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- HY-118754
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- HY-135385
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- HY-N6787S
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dihydrothymine-d6
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Endogenous Metabolite
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Metabolic Disease
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5,6-Dihydro-5-methyluracil-d6 is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].
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- HY-107670
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DHβE hydrobromide
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nAChR
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Neurological Disease
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Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities .
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- HY-114656
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dihydroprostaglandin F1α
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Others
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Endocrinology
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Dihydro-PGF1α is a potential metabolite of PGF1α .
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- HY-N1753
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dihydro-p-coumaryl alcohol; 3-(p-Hydroxyphenyl)propyl alcohol
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3-(4-Hydroxyphenyl)-1-propanol is used in the synthesis of (-)-centrolobine.
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- HY-41880S
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dihydro-2H-pyran-2,6(3H)-dione-d6; dihydro-3H-pyran-2,6-dione-d6; Glutaric acid anhydride-d6
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Isotope-Labeled Compounds
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Others
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Glutaric anhydride-d6 is the deuterium labeled Glutaric anhydride[1].
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- HY-135021
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5-HT Receptor
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Others
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3,4-Dihydro Naratriptan is a serotonin 5-HT1-receptor agonist. 3,4-Dihydro Naratriptan exhibits selective vasoconstrictor activity. 3,4-Dihydro Naratriptan can be used for migraine diseases research .
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- HY-114862
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13,14-dihydro-15(R)-PGE1
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Endogenous Metabolite
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Others
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13,14-dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)- PGE1) is an analog of 13,14-dihydro- PGE1 which has the hydroxyl group at C-15 in the unnatural R configuration .
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- HY-142180S
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- HY-N10350
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Others
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Cancer
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2,3-Dihydro-3-methoxywithaferin A is an analogue of 2,3-dihydrowithaferin-A. 2,3-Dihydro-3-methoxywithaferin A inhibits proiiferation of P388 cells[1].
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- HY-144235S
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- HY-N9301
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Others
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Others
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11,12-Dihydro-7-hydroxyhedychenone (compound 11) is a natural compound .
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- HY-118830
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DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-dihydro-15-keto-PGD2
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Prostaglandin Receptor
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Endocrinology
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13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation .
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- HY-N10748
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Others
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Cancer
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2',3'-Dihydro-2'-hydroxyprotoapigenone is a natural protoflavonoid found in ferns impair .
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- HY-N10091
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Apoptosis
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Others
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2,3-Dihydro-3α-methoxynimbolide is a limonoid compound isolated from the extracts of bark, leaves, roots, and seeds of Azadirachta indica A. Juss. var. siamensis Valeton. 2,3-Dihydro-3α-methoxynimbolide exhibits potent cyto-toxicities against one or more cell lines. 2,3-Dihydro-3α-methoxynimbolide activates caspases-3, -8, and -9, while increases the ratio of Bax/Bcl-2. 2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in AZ521 .
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- HY-N9088
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- HY-W010130
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3,4-dihydro-7-hydroxy-2(1H)-quinolinone
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Monoamine Oxidase
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Neurological Disease
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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B .
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- HY-137591
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Others
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Endocrinology
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13,14-Dihydro-15-keto-PGE1 is an inactive metabolite of PGE1. 13, 14-Dihydro-15-Keto-pGE1 inhibited platelet aggregation in ADP-induced human isolated platelet-rich plasma with IC50 14.8 μg/mL .
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- HY-113254S1
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- HY-113254S
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- HY-147178
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Others
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Others
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C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain .
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- HY-113461
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Others
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Others
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13,14-Dihydro-15-keto-prostaglandin A2 is a product of the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2. It is further broken down into bicyclo PGE2, which acts as a biomarker for PGE2 synthesis .
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- HY-W319671S
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- HY-130484
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Parasite
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2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
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- HY-163373
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Others
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13,14-Dihydro-15-keto prostaglandin D1 is a derivative of prostaglandin D1 .
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- HY-N8888
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Others
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Others
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10,11-Dihydro-24-hydroxyaflavinine (10,23,24,25-tetrahydro-24-hydroxyaflavinine), an aflavinine analog, is a natural product that can be isolated from Ascostromata of Eupenicillium crustaceum .
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- HY-W008646
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- HY-116083
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Endogenous Metabolite
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Others
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13,14-Dihydro-15-keto-tetranor prostaglandin D2 (Compound VI) is a prostaglandin D2 metabolite. 13,14-Dihydro-15-keto-tetranor prostaglandin D2 as a biomarker can be used to study prostaglandin D2-related diseases .
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- HY-78667
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Biochemical Assay Reagents
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Others
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6,7-Dihydro-4-benzo[b]thiophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-N10676
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Others
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Cancer
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8,8a-Dihydro-8-hydroxygambogic acid is a natural product, that can be isolated from the resin of Garcinia hanburyi. 8,8a-Dihydro-8-hydroxygambogic acid shows anticancer activity .
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- HY-113208
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Endogenous Metabolite
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Others
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13,14-Dihydro-15-keto PGF2a is an endogenous metabolite present in Blood that can be used for the research of Pregnancy .
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- HY-W756041
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rel-(1S,2S)-dihydro bupropion-d9 hydrochloride
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Isotope-Labeled Compounds
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Others
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rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride is the deuterium labeled rel-(1S,2S)-Dihydro bupropion hydrochloride.
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- HY-34692
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(3,4-Dihydro-2H-pyran-2-yl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-152352
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Nucleoside Antimetabolite/Analog
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Cancer
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7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-113208AS1
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- HY-W867679S
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- HY-77434
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9-DHAB III; 13-Acetyl-9-dihydrobaccatin III
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Others
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Cancer
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9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.
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- HY-W745349
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- HY-113113
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13,14-dihydroprostaglandin E1
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Endogenous Metabolite
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Metabolic Disease
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13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma) .
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- HY-139968S
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Isotope-Labeled Compounds
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Others
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13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 is the deuterium labeled 13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1[1].
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- HY-34097
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5-Bromo-2,3-dihydro-1H-isoindol-1-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-154284
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Nucleoside Antimetabolite/Analog
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Cancer
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7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152347
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Nucleoside Antimetabolite/Analog
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Cancer
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1-Amino-3’-deoxy-7,8-dihydro-8-oxoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-N0975
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Others
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Metabolic Disease
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1,11b-Dihydro-11b-hydroxymaackiain, a pterocarpane extract from the stems of Erycibe expansa, show a hepatoprotective effect .
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- HY-152338
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Nucleoside Antimetabolite/Analog
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Cancer
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7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152385
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Nucleoside Antimetabolite/Analog
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Others
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5,6-Dihydro-ara-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152364
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Nucleoside Antimetabolite/Analog
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Cancer
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7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152604
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Nucleoside Antimetabolite/Analog
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Others
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3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152824
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Nucleoside Antimetabolite/Analog
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Others
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(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152373
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Nucleoside Antimetabolite/Analog
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Cancer
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7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-N1772
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(3S,4S)-3,4-Dihydro-3,4-dihydroxynaphthalen-1(2H)-one (compound 9) is α-tetralone galloylglucoside that can be isolated from Juglans sigillata .
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- HY-152407
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Nucleoside Antimetabolite/Analog
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Others
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7-Allyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152431
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Nucleoside Antimetabolite/Analog
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Others
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1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152436
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Nucleoside Antimetabolite/Analog
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Others
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7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152328
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Nucleoside Antimetabolite/Analog
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Cancer
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7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152381
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Nucleoside Antimetabolite/Analog
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Cancer
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1,9-Dihydro-9-β-D-xylofuranosyl-6H-purin-6-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154283
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Nucleoside Antimetabolite/Analog
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Cancer
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2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-152341
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Nucleoside Antimetabolite/Analog
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Cancer
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7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W053705
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- HY-N9303
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- HY-152491
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Nucleoside Antimetabolite/Analog
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Others
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7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152333
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Nucleoside Antimetabolite/Analog
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Cancer
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7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152331
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Nucleoside Antimetabolite/Analog
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Cancer
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7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-D1507
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Fluorescent Dye
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Others
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1-[3-(Succinimidyloxycarbonyl)benzyl]-4-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)-5-oxazolyl]pyridinium bromide is a fluorescence dye .
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- HY-154425
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Nucleoside Antimetabolite/Analog
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Others
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2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-105000S1
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Isotope-Labeled Compounds
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Others
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trans-Dihydro Tetrabenazine-d7 is deuterium labeled (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol.
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- HY-152432
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Nucleoside Antimetabolite/Analog
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Others
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1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-N10885
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Others
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Others
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α,β-Dihydro-4,6-dihydroxy-2-methoxy-3-methylchalcone (compound 7) is a nature product that could be isolated from dragons blood of Daemonorops draco .
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- HY-N9300
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Others
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Inflammation/Immunology
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1,6-Dihydro-4,7-epoxy-1-methoxy-3,4-methylenedioxy-6-oxo-3,8-lignan, a lignan derivative from the ethyl acetate soluble fraction of twigs of Magnolia denudate (Magnoliaceae), exhibits anti-platelet-activating factor (PAF) activity. PAF is a potent lipid mediator in inflammation and asthma .
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- HY-W140284S
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Isotope-Labeled Compounds
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Others
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6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
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- HY-152703
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Nucleoside Antimetabolite/Analog
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Others
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2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine (G159-82) PTPD-2 Confidential is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152405
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Nucleoside Antimetabolite/Analog
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Others
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6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152616
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Nucleoside Antimetabolite/Analog
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Others
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2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-135794
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11-KDHT; 5α-dihydro-11-keto testosterone
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Androgen Receptor
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Endocrinology
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11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells .
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- HY-146708S
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Isotope-Labeled Compounds
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Others
|
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 15N4 (sodium) is a 15N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so
|
-
- HY-N10639
-
|
Others
|
Others
|
(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical .
|
-
- HY-W068697
-
Vinylacetic acid
|
Others
|
Others
|
3-Butenoic acid (Vinylacetic acid) can be used to synthesize bicyclic 3,6-dihydro-1,2-oxazine. Strained bicyclic 3,6-dihydro-1,2-oxazine is a reactive substrate in domino metathesis with an external alkene .
|
-
- HY-N0976
-
11b-Hydroxy-11b,1-dihydromedicarpin
|
Interleukin Related
|
Inflammation/Immunology
|
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .
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-
- HY-135794S
-
11-KDHT-d3; 5α-dihydro-11-keto testosterone-d3
|
Androgen Receptor
|
Endocrinology
|
11-Ketodihydrotestosterone-d3 is the deuterium labeled 11-Ketodihydrotestosterone. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells[1][2].
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-
- HY-118116
-
bicyclo-PGEM; bicyclo-Prostaglandin E2
|
Others
|
Others
|
bicyclo-PGE2 (bicyclo-PGEM) is a stable decomposition product of PGE2 and 13, 14-dihydro-15-ketone PGE2 .
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-
- HY-76487
-
|
Biochemical Assay Reagents
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Others
|
Dihydro-2H-pyran-4(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002623
-
|
Biochemical Assay Reagents
|
Others
|
2,3-Dihydro-1,4-benzodioxine-6-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012991
-
|
Biochemical Assay Reagents
|
Others
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002530
-
|
Biochemical Assay Reagents
|
Others
|
(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-157925
-
Bicyclo Prostaglandin E1
|
Others
|
Others
|
Bicyclo-PGE1 (Bicyclo Prostaglandin E1) is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. Bicyclo-PGE1 can be used to estimate the biosynthesis and metabolism of PGE1 in vivo .
|
-
- HY-N6619A
-
-
- HY-N6619
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Lycoramine hydrobromide, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine hydrobromide is a potent acetylcholinesterase (AChE) inhibitor .
|
-
- HY-132994
-
|
Others
|
Others
|
TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate .
|
-
- HY-149975
-
|
iGluR
|
Neurological Disease
|
AMPA receptor modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), is an orally active positive allosteric modulator of the AMPA receptors (AMPAR PAMs). AMPA receptor modulator-4 can cross the blood-brain barrier. AMPA receptor modulator-4 increases the cognition performance and improves working memory performance in mice .
|
-
- HY-D1576
-
|
Fluorescent Dye
|
Others
|
C6 NBD L-threo-dihydroceramide is a dihydro-ceramide isomer labeled with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD), can be used to detect ceramide.
|
-
- HY-43066
-
|
DNA/RNA Synthesis
|
Others
|
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((E)-(dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-W002530A
-
|
Others
|
Others
|
(1R,2R)-1-Aminoindan-2-ol is the isomer of (1S,2R)-1-Aminoindan-2-ol (HY-W002530), and can be used as an experimental control. (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76194A
-
3,4-dihydro-1(2H)-naphthalenone
|
Biochemical Assay Reagents
|
Others
|
3,4-Dihydronaphthalen-1-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W334680
-
|
Nucleoside Antimetabolite/Analog
|
Others
|
2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W127822
-
(1Z,4Z,10Z,15Z)-5,10,15-Triphenyl-22,24-dihydro-21H-corri
|
Biochemical Assay Reagents
|
Others
|
5,10,15-tris(phenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.
|
-
- HY-W127824
-
(5Z,9Z,14Z)-5,10,15-Tris(4-nitrophenyl)-22,24-dihydro-21H-corri
|
Biochemical Assay Reagents
|
Others
|
5,10,15-tris(4-nitrophenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.
|
-
- HY-34123S
-
2-(2-Bromoethyl)-1H-isoindole-1,3(2H)-dione-d4; 1-Bromo-2-phthalimidoethane-d4; 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl bromide-d4; 2-(2-Bromoethyl)-2,3-dihydro-1H-isoindole-1,3-dione
|
Isotope-Labeled Compounds
|
Others
|
N-(2-Bromoethyl)phthalimide-d4 is the deuterium labeled N-(2-Bromoethyl)phthalimide[1].
|
-
- HY-W357201
-
N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W415119
-
acetic acid 4-acetoxy-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydrofuran-3-yl ester
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
2',3'-Di-O-acetyl-D-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-78667
-
|
Biochemical Assay Reagents
|
6,7-Dihydro-4-benzo[b]thiophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76487
-
|
Biochemical Assay Reagents
|
Dihydro-2H-pyran-4(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002623
-
|
Biochemical Assay Reagents
|
2,3-Dihydro-1,4-benzodioxine-6-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012991
-
|
Biochemical Assay Reagents
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002530
-
|
Biochemical Assay Reagents
|
(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76194A
-
3,4-dihydro-1(2H)-naphthalenone
|
Biochemical Assay Reagents
|
3,4-Dihydronaphthalen-1-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127822
-
(1Z,4Z,10Z,15Z)-5,10,15-Triphenyl-22,24-dihydro-21H-corri
|
Biochemical Assay Reagents
|
5,10,15-tris(phenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.
|
-
- HY-W127824
-
(5Z,9Z,14Z)-5,10,15-Tris(4-nitrophenyl)-22,24-dihydro-21H-corri
|
Biochemical Assay Reagents
|
5,10,15-tris(4-nitrophenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.
|
Cat. No. |
Product Name |
Target |
Research Area |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Compare |
Product Name |
Species |
Source |
Compare Products
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Free Sample |
Yes
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* This product has been "discontinued".
Optimized version of product available:
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-146770S
-
|
Dihydro FF-MAS-d6 is deuterium labeled Dihydro FF-MAS.
|
-
-
- HY-146775S
-
|
Dihydro T-MAS-d6 is deuterium labeled Dihydro T-MAS.
|
-
-
- HY-N6787S
-
|
5,6-Dihydro-5-methyluracil-d6 is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].
|
-
-
- HY-41880S
-
|
Glutaric anhydride-d6 is the deuterium labeled Glutaric anhydride[1].
|
-
-
- HY-142180S
-
|
cis (2,3)-Dihydro tetrabenazine-d6 is the deuterium labeled cis (2,3)-Dihydro tetrabenazine[1].
|
-
-
- HY-144235S
-
|
cis-Dihydro Tetrabenazine-d7 is the deuterium labeled cis-Dihydro Tetrabenazine[1].
|
-
-
- HY-113254S1
-
|
13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2[1].
|
-
-
- HY-113254S
-
|
13,14-Dihydro-15-keto-PGE2-d4 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2[1].
|
-
-
- HY-W319671S
-
|
2-Methoxy-4,5-dihydro-1H-imidazole-d4 is the deuterium labeled 2-Methoxy-4,5-dihydro-1H-imidazole[1].
|
-
-
- HY-W756041
-
|
rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride is the deuterium labeled rel-(1S,2S)-Dihydro bupropion hydrochloride.
|
-
-
- HY-113208AS1
-
|
11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4 is is the deuterium labeled 11β-13,14-dihydro-15-keto Prostaglandin F2α.
|
-
-
- HY-W867679S
-
|
5,12-Dihydro-12-phenylindolo[3,2-a]carbazole-d16 is a deuterium labeled compound.
|
-
-
- HY-W745349
-
|
rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride is the deuterium labeled rel-(1S,2R)-Dihydro bupropion hydrochloride .
|
-
-
- HY-139968S
-
|
13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 is the deuterium labeled 13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1[1].
|
-
-
- HY-105000S1
-
|
trans-Dihydro Tetrabenazine-d7 is deuterium labeled (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol.
|
-
-
- HY-W140284S
-
|
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride[1].
|
-
-
- HY-146708S
-
|
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 15N4 (sodium) is a 15N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so
|
-
-
- HY-135794S
-
|
11-Ketodihydrotestosterone-d3 is the deuterium labeled 11-Ketodihydrotestosterone. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells[1][2].
|
-
-
- HY-34123S
-
|
N-(2-Bromoethyl)phthalimide-d4 is the deuterium labeled N-(2-Bromoethyl)phthalimide[1].
|
-
Cat. No. |
Product Name |
Application |
Reactivity |
-
- HY-P81140
-
8-hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7,8-dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG; 2'-Deoxy-8-hydroxyguanosine;
|
ELISA; IHC-P; IHC-F; IF
|
Human |
8-OHdG (DNA/RNA Damage) Antibody is an unconjugated, approximately 0.283 kDa, rabbit-derived, anti-8-OHdG (DNA/RNA Damage) polyclonal antibody. 8-OHdG (DNA/RNA Damage) Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, background without labeling.
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-152352
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154284
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152338
-
|
|
Alkynes
|
7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152364
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-152373
-
|
|
Alkynes
|
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154283
-
|
|
Alkynes
|
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-154425
-
|
|
Alkynes
|
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
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