5,6-Dihydro-5-methyluracil-d6
Based on 1 Customer Validation
5,6-Dihydro-5-methyluracil (Dihydrothymine)-d6 is the deuterium labeled 5,6-Dihydro-5-methyluracil (HY-N6787). 5,6-Dihydro-5-methyluracil is an intermediate breakdown product of Thymine (HY-W010450). 5,6-Dihydro-5-methyluracil can be used as a marker of DNA damage. 5,6-Dihydro-5-methyluracil can be used for the research of COVID-19.
For research use only. We do not sell to patients.
- Purity: 99%
- CAS No.: 334473-42-6
- Formula: C5H2D6N2O2
- Molecular Weight:134.17
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 334473-42-6
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Unlabeled Cas 696-04-8
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Appearance Solid
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Molecular Weight 134.17
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Formula C5H2D6N2O2
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Color White to off-white
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SMILES
O=C1C(C([2H])([2H])NC(N1)=O)([2H])C([2H])([2H])[2H]
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Synonyms
Dihydrothymine-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. de Fátima Cobre A, et al. Diagnosis and prognosis of COVID-19 employing analysis of patients' plasma and serum via LC-MS and machine learning. Comput Biol Med. 2022 Jul;146:105659. [Content Brief]
[2]. Dawidzik JB, et al. Dihydrothymine lesion in X-irradiated DNA: characterization at the molecular level and detection in cells. Int J Radiat Biol. 2004;80(5):355-361. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5,6-Dihydro-5-methyluracil-d6 Related Classifications
HY-N6787S Related Classifications
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