2,3-Dehydro-3,4-dihydro ivermectin
2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
For research use only. We do not sell to patients.
- CAS No.: 1135339-49-9
- Formula: C48H74O14
- Molecular Weight:875.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | IC50 |
65.5 μM
Compound: 5, delta2,3-IVM
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Cytotoxicity against mouse peritoneal macrophages assessed as LDH release after 48 hrs
Cytotoxicity against mouse peritoneal macrophages assessed as LDH release after 48 hrs
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[PMID: 19114308] |
Chemical Information
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CAS No. 1135339-49-9
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Molecular Weight 875.09
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Formula C48H74O14
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SMILES
O[C@]1(C(C(O[C@]2([H])C[C@](O[C@]3([H])[C@@H](C)CC)(CC[C@@H]3C)O[C@@](C/C=C4\C)([H])C2)=O)=C[C@@H]5C)[C@]([C@@H]5O)([H])OC/C1=C\C=C\[C@@H]([C@@H]4O[C@H](O[C@H]6C)C[C@@H]([C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)OC)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2,3-Dehydro-3,4-dihydro ivermectin Related Classifications
HY-130484 Related Classifications
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