1. Anti-infection
  2. Parasite
    SARS-CoV
  3. Ivermectin B1b

Ivermectin B1b 

Cat. No.: HY-125729
Handling Instructions

Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture.

For research use only. We do not sell to patients.

Ivermectin B1b Chemical Structure

Ivermectin B1b Chemical Structure

CAS No. : 70209-81-3

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Description

Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture[1][2].

In Vitro

Ivermectin and Ivermectin B1b are the most potent inhibitors of contraction and motility in both susceptible isolates (H. contortus McMaster and and O. circumcincta McMaster) also show the highest resistance ratios in both species[3].
Vermectin is a macrocyclic lactone that acts as a positive allosteric modulator of α7 nicotinic acetylcholine receptors (nAChRs) but has no modulatory activity on 5-HT3 receptors[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ivermectin B1b causes snail death[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

861.07

Formula

C₄₇H₇₂O₁₄

CAS No.

70209-81-3

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Ivermectin B1bParasiteSARS-CoVSARS coronaviruscontractionmotilityantiparasiticneuronsmusclecellsSARS-CoV-2COVID-19Inhibitorinhibitorinhibit

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Ivermectin B1b
Cat. No.:
HY-125729
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