rel-(1S,2R)-Dihydro bupropion-d₉ hydrochloride 

rel-(1S,2R)-Dihydro bupropion-d₉ hydrochloride is the deuterium labeled rel-(1S,2R)-Dihydro bupropion hydrochloride (HY-178240). rel-(1S,2R)-Dihydro bupropion is a metabolite of bupropion. rel-(1S,2R)-Dihydro bupropion can promote endogenous IL-10 production and inhibit Th1 cytokines (IL-12 and TNF-α). rel-(1S,2R)-Dihydro bupropion can induce immune response transition from Th1 to Th2. rel-(1S,2R)-Dihydro bupropion can be used for research on inflammatory conditions^[1].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

287.27

C₁₃H₁₂D₉Cl₂NO

2517771-79-6

[2H]C(C(C([2H])([2H])[2H])(N[C@@H]([C@H](C1=CC(Cl)=CC=C1)O)C)C([2H])([2H])[2H])([2H])[2H].Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Robin Mark Bannister, et al. Treatment of Th-1 mediated inflammatory diseases using bupropion and metabolites thereof. WO2012056229.