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Cat. No.: HY-W777138

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rel-(1S,2R)-Dihydro bupropion-d₉

Name: rel-(1S,2R)-Dihydro bupropion-d9
Brand: MedChemExpress
SKU: HY-W777138
Price: 951.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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rel-(1S,2R)-Dihydro bupropion-d₉ is the deuterium labeled rel-(1S,2R)-Dihydro bupropion (HY-178240). rel-(1S,2R)-Dihydro bupropion is a metabolite of bupropion. rel-(1S,2R)-Dihydro bupropion can promote endogenous IL-10 production and inhibit Th1 cytokines (IL-12 and TNF-α). rel-(1S,2R)-Dihydro bupropion can induce immune response transition from Th1 to Th2. rel-(1S,2R)-Dihydro bupropion can be used for research on inflammatory conditions.

For research use only. We do not sell to patients.

CAS No.: 1217684-77-9
Formula: C₁₃H₁₁D₉ClNO
Molecular Weight:250.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

rel-(1S,2R)-Dihydro bupropion-d₉ Chemical Structure

CAS No.: 1217684-77-9

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Biological Activity
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Chemical Information
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Biological Activity

Description

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All TNF Receptor Isoforms :

All Interleukin Related Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1217684-77-9
Unlabeled CAS 99102-04-2
Molecular Weight 250.81
Formula C₁₃H₁₁D₉ClNO
SMILES

[2H]C([2H])([2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])N[C@H](C)[C@H](C1=CC(Cl)=CC=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Robin Mark Bannister, et al. Treatment of Th-1 mediated inflammatory diseases using bupropion and metabolites thereof. WO2012056229.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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rel-(1S,2R)-Dihydro bupropion-d9

All Endogenous Metabolite Isoforms

All TNF Receptor Isoforms

All Interleukin Related Isoforms