β-Glycerophosphate disodium salt hydrate

Name: β-Glycerophosphate disodium salt hydrate
Brand: MedChemExpress
SKU: HY-126304
Rating: 5.0 (30 reviews)

Cat. No.: HY-126304 Pureté: 99.92%: Fiche technique
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β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells.

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CAS No. : 154804-51-0

Size	Stock	Quantité
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
10 g	En stock	Estimated Time of Arrival: December 31
25 g	En stock	Estimated Time of Arrival: December 31
50 g	En stock	Estimated Time of Arrival: December 31
> 100 g	Obtenir un devis

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Based on 30 publication(s) in Google Scholar

Other Forms of β-Glycerophosphate disodium salt hydrate:

Glycerophosphoric acid disodium salt hydrate (α and β mixture) In-stock
β-Glycerophosphate disodium salt pentahydrate In-stock
β-Glycerophosphate disodium salt hydrate (Standard) In-stock

30 Publications Citing Use of MCE β-Glycerophosphate disodium salt hydrate

Cell Imaging/Staining

: β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Jun 21:33:102009. [Abstract]; β-Glycerophosphate disodium salt pentahydrate (10 mM; 1 week). DPA@NM@CTZE boosts the mineralization and differentiation capabilities of osteoblasts in a palmitic acid (Pa) environment.

: β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: Biomaterials. 2024 Aug 15:313:122756. [Abstract]; Representative images of Alizarin Red staining on 14 and 21 days of BMSCs seeded on porous tantalum scaffolds and cultured in osteogenic induction medium containing 1 M β-glycerophosphate (β-Glycerophosphate disodium salt pentahydrate) and 10 mM ascorbic acid ( L-Ascorbic acid).

: β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Mol Histol. 2024 Aug;55(4):503-512.; β-Glycerophosphate disodium salt pentahydrate (10 mM; 7-21 days). The expression levels of KLF9 (shown by immunofluorescence staining) under different induction conditions.

: β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2023 May 18:20:100667.; β-Glycerophosphate disodium salt pentahydrate (10 mM; 7 days). Representative ALP staining image of BMSCs cultured on Gyroid, Cylindrical, Cubic pore scaffolds and Control in the osteogenic medium after culturing for 7 days.

: β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Mol Histol. 2021 Oct;52(5):1067-1080. [Abstract]; β-Glycerophosphate disodium salt pentahydrate (10 mM; 48 h). Western blot showed that the expression of ALP, BMP2, phosphorylation-STAT3 and STAT3 protein in VSMCs treated by different chemical compound.

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Activité biologique
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Description

IC₅₀ & Target

ERK1

ERK2

In Vitro

β-Glycerophosphate disodium salt pentahydrate, as a phosphate source of the bone mineral hydroxyapatite, can promote osteogenic differentiation and further induce osteogenic gene expression through phosphorylation of the cytokinase-associated kinase ERK1/2^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formule

C₃H₇O₆PNa₂.xH₂O

CAS No.

154804-51-0

Appearance

Solid

Color

White to off-white

SMILES

OCC(OP(O[Na])(O[Na])=O)CO.[H]O[H].[x]

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvant et solubilité

In Vitro:

H₂O : 175 mg/mL (Need ultrasonic)

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 25 mg/mL; Clear solution; Need ultrasonic and warming

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureté et documentation

Purity: 99.92%

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Fiche technique (276 KB) SDS (393 KB)

COA (253 KB) HNMR (252 KB) RP-HPLC (253 KB) MS (70 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Belfield A, et al. Inhibition of the nucleotidase effect of alkaline phosphatase by beta-glycerophosphate. Nature. 1968 Jul 6;219(5149):73-5. [Content Brief]

[2]. Shioi A, et al. Beta-glycerophosphate accelerates calcification in cultured bovine vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1995 Nov;15(11):2003-9. [Content Brief]

[3]. Langenbach F, et al. Effects of dexamethasone, ascorbic acid and β-glycerophosphate on the osteogenic differentiation of stem cells in vitro. Stem Cell Res Ther. 2013;4(5):117.