2. Anti-infection TGF-beta/Smad Epigenetics
  3. PKC HIV
  4. HIV-1 protease-IN-10

HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity (IC50: 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain (IC50: 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis.

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HIV-1 protease-IN-10

HIV-1 protease-IN-10 화학구조

CAS No. : 2982527-11-5

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HIV-1 protease-IN-10 Related Antibodies

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제품 설명

HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity (IC50: 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain (IC50: 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis[1].

Cellular Effect
Cell Line Type Value Description References
Jurkat CC50
>10 3
Compound: 2
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by Ghost dye 780 staining based flow cytometric analysis
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by Ghost dye 780 staining based flow cytometric analysis
[PMID: 37224601]
Jurkat CC50
> 10 3
Compound: 2
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by Ghost dye 780 staining based flow cytometric analysis
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by Ghost dye 780 staining based flow cytometric analysis
[PMID: 37224601]
분자량

396.56

화학식

C23H40O5
CAS No.
SMILES

O=C1OC(CO)(COC(C(CCCCCC)CCCCCC)=O)C/C1=C(C)/C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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HIV-1 protease-IN-10 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1 protease-IN-102982527-11-5PKCHIVProtein kinase CHuman immunodeficiency virusLRAslatency reversing agentsC1b domainlatencyantiviralinfectionInhibitorinhibitorinhibit

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HIV-1 protease-IN-10
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HY-155599
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