Rhapontigenin 3'-O-glucoside

Name: Rhapontigenin 3'-O-glucoside
Brand: MedChemExpress
SKU: HY-N2233
Rating: 4.5 (1 reviews)

製品番号: HY-N2233 純度: 99.94%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent.

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Rhapontigenin 3'-O-glucoside 構造式

CAS 番号 : 94356-22-6

容量	価格（税別）	在庫状況	数量
1 mg	$95	在庫あり	Estimated Time of Arrival: December 31
5 mg	$240	在庫あり	Estimated Time of Arrival: December 31
10 mg		お問い合わせ
50 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

顧客検証

•Biomed Res Int. 2021 Sep 9;2021:9066938. [Abstract]

Cytochrome P450 アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent^[1].

体外実験

Rhapontigenin exhibits a potent and selective inhibition of human P450 1A1 with an IC₅₀ of 0.4 μM. Rhapontigenin shows 400-fold selectivity for P450 1A1 over P450 1A2 and 23-fold selectivity for P450 1A1 over P450 1B1^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

420.41

分子式

C₂₁H₂₄O₉

CAS 番号

94356-22-6

Appearance

Solid

Color

Off-white to gray

SMILES

O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC(/C=C/C3=CC(O)=CC(O)=C3)=CC=C2OC

Structure Classification

Stilbenes

Initial Source

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (237.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3786 mL	11.8932 mL	23.7863 mL
5 mM	0.4757 mL	2.3786 mL	4.7573 mL
10 mM	0.2379 mL	1.1893 mL	2.3786 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.94%

Select Batch:

データシート (274 KB) SDS (252 KB)

COA (254 KB) HNMR (288 KB) CNMR (270 KB) RP-HPLC (96 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Chun YJ, et al. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin. Drug Metab Dispos. 2001 Apr;29(4 Pt 1):389-93. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.3786 mL	11.8932 mL	23.7863 mL	59.4658 mL
	5 mM	0.4757 mL	2.3786 mL	4.7573 mL	11.8932 mL
	10 mM	0.2379 mL	1.1893 mL	2.3786 mL	5.9466 mL
	15 mM	0.1586 mL	0.7929 mL	1.5858 mL	3.9644 mL
	20 mM	0.1189 mL	0.5947 mL	1.1893 mL	2.9733 mL
	25 mM	0.0951 mL	0.4757 mL	0.9515 mL	2.3786 mL
	30 mM	0.0793 mL	0.3964 mL	0.7929 mL	1.9822 mL
	40 mM	0.0595 mL	0.2973 mL	0.5947 mL	1.4866 mL
	50 mM	0.0476 mL	0.2379 mL	0.4757 mL	1.1893 mL
	60 mM	0.0396 mL	0.1982 mL	0.3964 mL	0.9911 mL
	80 mM	0.0297 mL	0.1487 mL	0.2973 mL	0.7433 mL
	100 mM	0.0238 mL	0.1189 mL	0.2379 mL	0.5947 mL