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Results for "

NO-red

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Antibiotic (2) Apoptosis (4) Arginase (3) Bacterial (6) EBV (2) Epoxide Hydrolase (1) Fluorescent Dye (2) Fungal (1) Glutaminase (1) GSK-3 (1) HSV (3) Influenza Virus (1) Isotope-Labeled Compounds (3) mAChR (1) Mitophagy (1) Monoamine Oxidase (2) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) Parasite (3) Phosphodiesterase (PDE) (1) PPAR (2) Progesterone Receptor (1) Ras (2) Reactive Oxygen Species (1) TRP Channel (2)
By Research Areas:	Cancer (8) Endocrinology (1) Infection (11) Inflammation/Immunology (3) Metabolic Disease (4) Neurological Disease (9)

By Targets:

5-HT Receptor (2)

Antibiotic (2)

Apoptosis (4)

Arginase (3)

Bacterial (6)

EBV (2)

Epoxide Hydrolase (1)

Fluorescent Dye (2)

Fungal (1)

Glutaminase (1)

GSK-3 (1)

HSV (3)

Influenza Virus (1)

Isotope-Labeled Compounds (3)

mAChR (1)

Mitophagy (1)

Monoamine Oxidase (2)

Nucleoside Antimetabolite/Analog (1)

Opioid Receptor (1)

Parasite (3)

Phosphodiesterase (PDE) (1)

PPAR (2)

Progesterone Receptor (1)

Ras (2)

Reactive Oxygen Species (1)

TRP Channel (2)

By Research Areas:

Cancer (8)

Endocrinology (1)

Infection (11)

Inflammation/Immunology (3)

Metabolic Disease (4)

Neurological Disease (9)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: NO Synthase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1266

RB-OPD NO-red	Fluorescent Dye	Others
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .

HY-112885C

nor-NOHA dihydrochloride 1 Publications Verification Nω-Hydroxy-NOr-L-arginine dihydrochloride	Apoptosis Arginase	Metabolic Disease Inflammation/Immunology Cancer
nor-NOHA dihydrochloride is a selective and reversible arginase inhibitor. nor-NOHA dihydrochloride induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride can used in study endothelial dysfunction, immunosuppression and metabolism .

HY-N10851

23-Nor-6-oxopristimerol

Others Others

23-Nor-6-oxopristimerol is a phenolic dinor-triterpene .
HY-143542S

Nor neostigmine-d6

Isotope-Labeled Compounds Others

Nor neostigmine-d₆ is the deuterium labeled Nor neostigmine[1].
HY-132422S

Nor Lidocaine-d5 hydrochloride

Isotope-Labeled Compounds Others

Nor Lidocaine-d₅ (hydrochloride) is the deuterium labeled Nor Lidocaine hydrochloride[1].

*23-Nor-6-oxopristimerol*	Others	Others
23-Nor-6-oxopristimerol is a phenolic dinor-triterpene .

Nor neostigmine-d6	Isotope-Labeled Compounds	Others
Nor neostigmine-d₆ is the deuterium labeled Nor neostigmine[1].

Nor Lidocaine-d5 hydrochloride	Isotope-Labeled Compounds	Others
Nor Lidocaine-d₅ (hydrochloride) is the deuterium labeled Nor Lidocaine hydrochloride[1].

HY-112885B

nor-NOHA monoacetate 1 Publications Verification Nω-Hydroxy-NOr-L-arginine moNOacetate	Arginase	Metabolic Disease
nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .

HY-143665S

Nor-W-18-d4

Isotope-Labeled Compounds Others

Nor-W-18-d₄ is the deuterium labeled Nor-W-18[1].

Nor-W-18-d4	Isotope-Labeled Compounds	Others
Nor-W-18-d₄ is the deuterium labeled Nor-W-18[1].

HY-117040

nor-Binaltorphimine NOrbinaltorphimine; NOrBNI	Opioid Receptor	Others
nor-Binaltorphimine is a selective antagonist of kappa-opioid receptor. nor-Binaltorphimine has a long-lasting effect in vivo .

HY-N1602

16-Nor-15-oxodehydroabietic acid

Others Others

16-Nor-15-oxodehydroabietic acid (compound 32) is a compound isolated from the root bark of Pinus massoniana .

*16-Nor-15-oxodehydroabietic acid*	Others	Others
16-Nor-15-oxodehydroabietic acid (compound 32) is a compound isolated from the root bark of Pinus massoniana .

HY-146067

*β-Nor-lapachone*	Fungal Reactive Oxygen Species	Infection
β-Nor-lapachone is a *Candida glabrata* antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity .

HY-N1713

29-Nor-20-oxolupeol

29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC₅₀ of 44.21 µM .
HY-N1607

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one

Others Others

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one is a compound isolated from the buds of Pinus banksiana Lamb .
HY-N1594

15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid

15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound isolated from the roots of Chloranthus spicatus .

*29-Nor-20-oxolupeol*
29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC₅₀ of 44.21 µM .

*18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one*	Others	Others
18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one is a compound isolated from the buds of Pinus banksiana Lamb .

*15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid*
15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound isolated from the roots of Chloranthus spicatus .

HY-112885A

nor-NOHA acetate Nω-Hydroxy-NOr-L-arginine acetate	Arginase Apoptosis	Metabolic Disease Inflammation/Immunology Cancer
nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. Anti-leukemic activity, effective in endothelial dysfunction, immunosuppression and metabolism .

HY-B0132B

Norfloxacin (nicotinate) MK-0366 (nicotinate)	Bacterial Antibiotic	Infection
Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration .

HY-131101

Nor-Acetildenafil

Phosphodiesterase (PDE) Others

Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor .
HY-43711

Nor-benzetimide

mAChR Neurological Disease

Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity .

Nor-Acetildenafil	Phosphodiesterase (PDE)	Others
Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor .

Nor-benzetimide	mAChR	Neurological Disease
Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity .

HY-108357

*6-Diazo-5-oxo-L-nor-Leucine* 5+ Cited Publications L-6-Diazo-5-oxoNOrleucine; DON	Glutaminase Bacterial Influenza Virus Antibiotic	Infection Cancer
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .

HY-W670564A

*(4S)-10-Nor-calamenen-10-one*	Others	Neurological Disease
(4S)-10-Nor-calamenen-10-one (Compound 15) enhances LPS-induced NO production by microglia. (4S)-10-Nor-calamenen-10-one is an eudesmane sesquiterpene that can be isolated from Alpinia oxyphylla .

HY-N2944

Blumenol B

Others Others

Blumenol B, a C₁₃ nor-isoprenoid, can be isolated from the leaves of Casearia sylvestris .

Blumenol B	Others	Others
Blumenol B, a C₁₃ nor-isoprenoid, can be isolated from the leaves of Casearia sylvestris .

HY-100784

Dihydrokainic acid
Dihydrokainic acid (DHK) is a glutamate transporter GLT1 (EAAT2) inhibitor. Dihydrokainic acid impairs novel object recognition (NOR) memory performance in mice. Dihydrokainic acid also shows epileptogenic effects .

HY-N1609

18-Nor-abieta-8,11,13-triene-4,15-diol

18-Nor-abieta-8,11,13-triene-4,15-diol (Compound 20) is a natural product that can be isolated from Abies georgei .

*18-Nor-abieta-8,11,13-triene-4,15-diol*
18-Nor-abieta-8,11,13-triene-4,15-diol (Compound 20) is a natural product that can be isolated from Abies georgei .

HY-N8041

Mogroside III A2	HSV	Infection
Mogroside III A2 is a cucurbitane glycoside. Mogroside III A2 can inhibit Epstein-Barr virus early antigen (EBV-EA) activation. Mogroside III A2 shows weak inhibitory effects on activation of NOR 1 .

HY-D1509

Phenazine ethosulfate	Fluorescent Dye	Others
Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .

HY-N6641

Monascin	Others	Inflammation/Immunology Cancer
Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor) .

HY-146438

PPARγ agonist 3	PPAR	Cancer
PPARγ agonist 3 (Compound 18a) is a potent and selective agonist of PPARγ. PPARγ agonist 3 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 3 exerts antitumor potency only in combination with Imatinib .

HY-18832

AWL-II-38.3
AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf .

HY-146439

PPARγ agonist 4	PPAR	Cancer
PPARγ agonist 4 (Compound 18b) is a potent and selective agonist of PPARγ. PPARγ agonist 4 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 4 exerts antitumor potency only in combination with Imatinib .

HY-12949

ML204 4 Publications Verification	TRP Channel	Neurological Disease
ML204 is a potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca ²⁺ channels .

HY-149810

AcrB-IN-2	Bacterial Parasite	Infection
AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .

HY-12949A

ML204 hydrochloride 4 Publications Verification	TRP Channel	Neurological Disease
ML204 hydrochloride is a novel, potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca ²⁺ channels .

HY-122529

Almurtide	Bacterial	Infection
Almurtide (nor-MDP), a muramyl dipeptide derivative with anti-inflammatory and anti-tumor activity. Almurtide also shows protective effects against intraperitoneal Pseudomonas aeruginosa infection or intravenously Candida albicans infection in mice. Almurtide also inhibits the carcinogenic Friend leukemia virus .

HY-126326

SWE101	Epoxide Hydrolase	Metabolic Disease
SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC₅₀s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH .

HY-149811

AcrB-IN-3	Bacterial Parasite	Infection
Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .

HY-149812

AcrB-IN-4	Bacterial Parasite	Infection
Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .

HY-W703425

*17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one* delta-5(6)-NOrethindrone	Progesterone Receptor	Endocrinology
17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one (delta-5(6)-Norethindrone), an impurity of Norethindrone, is an anabolic agent. Norethindrone is a progestin athat can be used for endometriosis research .

HY-153089

GSK3-IN-3 1 Publications Verification	GSK-3 Mitophagy	Neurological Disease
GSK3-IN-3 is a mitophagy inducer, inducing Parkin-dependent mitophagy. GSK3-IN-3 is also a GSK-3 inhibitor with an IC₅₀ value of 3.01 μM. GSK3-IN-3 is non-ATP nor substrate competitive and is neuroprotective against 6-OHDA .

HY-12646

Rhosin hydrochloride Maximum Cited Publications 24 Publications Verification	Ras Apoptosis	Cancer
Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a K_d of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis . Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .

HY-12646A

Rhosin	Ras Apoptosis	Cancer
Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a K_d of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis . Rhosin promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .

HY-N7040

11-Deoxymogroside IIE	HSV	Infection
11-Deoxymogroside IIE is a cucurbitane glycoside, isolated from Siraitia grosvenorii fruits. 11-Deoxymogroside IIE has inhibitory effect against Epstein Barr virus (EBV-EA) activation induced by TPA, shows weak inhibitory effect on (+/-)-(E)-methyl1-2-[E-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR1), a NO donor .

HY-23789

2′-O-(2-Methoxyethyl)guanosine 2'-O-MOE-rG	Nucleoside Antimetabolite/Analog	Others
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .

HY-N7041

11-Oxomogroside IIa	EBV HSV	Infection
11-Oxomogroside IIa (11-oxomogroside II A1) is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. 11-Oxomogroside IIa has inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .

HY-N11009

11-Oxomogroside II A1	EBV	Infection
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .

HY-155330

PZ-1922	5-HT Receptor Monoamine Oxidase	Neurological Disease
PZ-1922 (Compound 16) is a BBB-penetrable 5-HT6R/5-HT3R antagonist (K_i: 17 nM, 0.45 nM for 5-HT6R/5-HT3R respectively). PZ-1922 reversibly inhibits MAO-B (pIC₅₀: 8.93). PZ-1922 reverses Scopolamine (SCOP) (HY-N0296) induced memory deficits in the novel object recognition (NOR) test in rats. PZ-1922 prevents Aβ-induced memory decline in the T-maze test .

HY-155330A

PZ-1922 free base	5-HT Receptor Monoamine Oxidase	Neurological Disease
PZ-1922 free base is a BBB-penetrable 5-HT6R/5-HT3R antagonist (K_i: 17 nM, 0.45 nM for 5-HT6R/5-HT3R respectively). PZ-1922 free base reversibly inhibits MAO-B (pIC₅₀: 8.93). PZ-1922 free base reverses Scopolamine (SCOP) (HY-N0296) induced memory deficits in the novel object recognition (NOR) test in rats. PZ-1922 free base prevents Aβ-induced memory decline in the T-maze test .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10851

*23-Nor-6-oxopristimerol*	Kokoona zeylanica Thwaites Triterpenes Structural Classification Terpenoids Source classification Celastraceae Plants	Others
23-Nor-6-oxopristimerol is a phenolic dinor-triterpene .