PZ-1922 free base
PZ-1922 free base is a BBB-penetrable 5-HT6R/5-HT3R antagonist (Ki: 17 nM, 0.45 nM for 5-HT6R/5-HT3R respectively). PZ-1922 free base reversibly inhibits MAO-B (pIC50: 8.93). PZ-1922 free base reverses Scopolamine (SCOP) (HY-N0296) induced memory deficits in the novel object recognition (NOR) test in rats. PZ-1922 free base prevents Aβ-induced memory decline in the T-maze test.
For research use only. We do not sell to patients.
- CAS No.: 1648745-65-6
- Formula: C22H21ClN4
- Molecular Weight:376.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 1648745-65-6
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Molecular Weight 376.88
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Formula C22H21ClN4
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SMILES
ClC1=CC=CC(CN2C=CC3=C2C4=C(C=CC=C4)N=C3N5CCNCC5)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)