1. Metabolic Enzyme/Protease
    Anti-infection
  2. Glutaminase
    Bacterial
    Influenza Virus
    Antibiotic
  3. 6-Diazo-5-oxo-L-nor-Leucine

6-Diazo-5-oxo-L-nor-Leucine (Synonyms: L-6-Diazo-5-oxonorleucine; DON)

Cat. No.: HY-108357 Purity: ≥95.0%
Handling Instructions

L-6-Diazo-5-oxonorleucine (L-6-Diazo-5-oxonorleucine) is a glutaminases antagonist with a Ki of 6 μM. L-6-Diazo-5-oxonorleucine exhibits analgesic, antibacterial, antiviral and anticancer properties. L-6-Diazo-5-oxonorleucine displays genetic toxicity in vitro. L-6-Diazo-5-oxonorleucine decreases the self-renewal potential and metastatic ability of tumor cell.

For research use only. We do not sell to patients.

6-Diazo-5-oxo-L-nor-Leucine Chemical Structure

6-Diazo-5-oxo-L-nor-Leucine Chemical Structure

CAS No. : 157-03-9

Size Price Stock Quantity
10 mM * 1 mL in Water USD 94 In-stock
Estimated Time of Arrival: December 31
1 mg USD 50 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

L-6-Diazo-5-oxonorleucine (L-6-Diazo-5-oxonorleucine) is a glutaminases antagonist with a Ki of 6 μM. L-6-Diazo-5-oxonorleucine exhibits analgesic, antibacterial, antiviral and anticancer properties. L-6-Diazo-5-oxonorleucine displays genetic toxicity in vitro. L-6-Diazo-5-oxonorleucine decreases the self-renewal potential and metastatic ability of tumor cell[1][2][3][4].

IC50 & Target

Ki: 6 μM (glutaminases)[4]

Molecular Weight

171.15

Formula

C₆H₉N₃O₃

CAS No.
SMILES

N[[email protected]@H](CCC(C=[N+]=[N-])=O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 83.33 mg/mL (486.88 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8428 mL 29.2141 mL 58.4283 mL
5 mM 1.1686 mL 5.8428 mL 11.6857 mL
10 mM 0.5843 mL 2.9214 mL 5.8428 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: ≥99.0%

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Keywords:

6-Diazo-5-oxo-L-nor-LeucineL-6-Diazo-5-oxonorleucine DONGlutaminaseBacterialInfluenza VirusAntibioticInhibitorinhibitorinhibit

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Product Name:
6-Diazo-5-oxo-L-nor-Leucine
Cat. No.:
HY-108357
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