1. Metabolic Enzyme/Protease
  2. Glutaminase
  3. JHU-083

JHU-083 

Cat. No.: HY-122218
Handling Instructions

JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells. Blocking the function of glutaminase by the glutamine antagonist JHU-083 in experimental cerebral malaria (ECM) can result in a net decrease of glutamate levels in the animals.

For research use only. We do not sell to patients.

JHU-083 Chemical Structure

JHU-083 Chemical Structure

CAS No. : 1998725-11-3

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Description

JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells[1]. Blocking the function of glutaminase by the glutamine antagonist JHU-083 in experimental cerebral malaria (ECM) can result in a net decrease of glutamate levels in the animals[2].

IC50 & Target

Glutamine[2]

Molecular Weight

312.36

Formula

C₁₄H₂₄N₄O₄

CAS No.

1998725-11-3

SMILES

O=C(OCC)[[email protected]](CCC(C=[N+]=[N-])=O)NC([[email protected]](CC(C)C)N)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
JHU-083
Cat. No.:
HY-122218
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