1. Metabolic Enzyme/Protease
  2. Glutaminase
  3. ZED-1227

ZED-1227 

Cat. No.: HY-19359
Handling Instructions

ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD).

For research use only. We do not sell to patients.

ZED-1227 Chemical Structure

ZED-1227 Chemical Structure

CAS No. : 1542132-88-6

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Description

ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1].

IC50 & Target

TG2[1]

Molecular Weight

528.60

Formula

C₂₆H₃₆N₆O₆

CAS No.

1542132-88-6

SMILES

O=C(OC)/C=C/CC[[email protected]](NC(C1=CN=CN1C)=O)C(NC2=CC=CN(CC(NCC(CC)CC)=O)C2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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ZED-1227
Cat. No.:
HY-19359
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