1. Biochemical Assay Reagents
  2. 2′-O-(2-Methoxyethyl)guanosine

2′-O-(2-Methoxyethyl)guanosine (Synonyms: 2'-O-MOE-rG)

Cat. No.: HY-23789
Handling Instructions

2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA.

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2′-O-(2-Methoxyethyl)guanosine Chemical Structure

2′-O-(2-Methoxyethyl)guanosine Chemical Structure

CAS No. : 473278-54-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA[1][2].

Molecular Weight

341.32

Formula

C₁₃H₁₉N₅O₆

CAS No.

473278-54-5

SMILES

COCCO[[email protected]]1[[email protected]@](N2C3=C(C(N=C(N3)N)=O)N=C2)([H])O[[email protected]@H]([[email protected]]1O)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (732.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9298 mL 14.6490 mL 29.2980 mL
5 mM 0.5860 mL 2.9298 mL 5.8596 mL
10 mM 0.2930 mL 1.4649 mL 2.9298 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (6.09 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (6.09 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.09 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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Keywords:

2′-O-(2-Methoxyethyl)guanosine2'-O-MOE-rGOthersnucleosideenzymaticconversionadenosinedeaminasephosphorylatedDNARNAInhibitorinhibitorinhibit

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Product Name:
2′-O-(2-Methoxyethyl)guanosine
Cat. No.:
HY-23789
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