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Results for "

enzymatic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) ADC Cytotoxin (1) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (2) Anaplastic lymphoma kinase (ALK) (2) Antibiotic (3) Antibody-Drug Conjugates (ADCs) (2) Apoptosis (11) Atg4 (1) ATGL (1) Autophagy (6) Bacterial (7) Bcr-Abl (1) Beta-secretase (1) Biochemical Assay Reagents (9) Bradykinin Receptor (1) Btk (1) c-Myc (1) Calcium Channel (1) Caspase (1) Cathepsin (1) CD38 (1) CDK (4) ClpP (1) Complement System (1) COX (1) Cytochrome P450 (1) DNA Alkylator/Crosslinker (1) DNA Stain (2) DNA/RNA Synthesis (3) E1/E2/E3 Enzyme (4) EGFR (3) Endogenous Metabolite (26) Eukaryotic Initiation Factor (eIF) (1) FLT3 (1) Fluorescent Dye (12) Fungal (1) GABA Receptor (1) GCGR (2) GLP Receptor (2) Glucocorticoid Receptor (1) Glucokinase (1) Glucosidase (2) HDAC (2) Histone Demethylase (4) Histone Methyltransferase (3) HIV (3) HIV Protease (3) HMG-CoA Reductase (HMGCR) (1) HSP (1) IKK (1) Indoleamine 2,3-Dioxygenase (IDO) (1) IRAK (1) Isotope-Labeled Compounds (6) Leukotriene Receptor (1) MALT1 (1) MAP4K (1) Microtubule/Tubulin (1) Mineralocorticoid Receptor (1) Mitochondrial Metabolism (1) MMP (1) Monoamine Oxidase (2) mTOR (1) NF-κB (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) P2Y Receptor (2) PAI-1 (2) Parasite (2) PARP (4) Phospholipase (1) PI3K (2) PPAR (2) Prostaglandin Receptor (2) PROTACs (1) PSMA (1) Pyruvate Kinase (1) RAR/RXR (4) Reactive Oxygen Species (1) Reverse Transcriptase (1) RIP kinase (1) SARS-CoV (5) Ser/Thr Protease (2) Sirtuin (2) Stearoyl-CoA Desaturase (SCD) (1) Trk Receptor (1) Tyrosinase (4) ULK (1) Virus Protease (1) Xanthine Oxidase (3) β-catenin (1)
By Research Areas:	Cancer (65) Cardiovascular Disease (8) Endocrinology (4) Infection (15) Inflammation/Immunology (22) Metabolic Disease (26) Neurological Disease (20)
Click Chemistry:	Azide (1)

197

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7264

7α-Hydroxycholesterol	Others	Metabolic Disease
7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation .

HY-133803

Z-Ala-Ala-OH

Amino Acid Derivatives Others

Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis .
HY-D1706

AMCA-6-dUTP

DNA Stain Others

AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA .

Z-Ala-Ala-OH	Amino Acid Derivatives	Others
Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis .

AMCA-6-dUTP	DNA Stain	Others
AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA .

HY-137421

4-Nitrophenyl N-acetyl-α-D-glucosaminide	Others	Others
4-Nitrophenyl N-acetyl-α-D-glucosaminide is a 4-nitrophenyl- conjugated substrate for determining the enzymatic specificity .

HY-P2344

HIV Protease Substrate 1

HIV Protease Infection

HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .
HY-P2344A

HIV Protease Substrate 1 TFA

HIV Protease Infection

HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

HIV Protease Substrate 1	HIV Protease	Infection
HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

HIV Protease Substrate 1 TFA	HIV Protease	Infection
HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

HY-125130

Hesperetin 7-O-glucoside	HMG-CoA Reductase (HMGCR) Bacterial	Infection Metabolic Disease
Hesperetin 7-O-glucoside is produced by the enzymatic conversion of Hesperidin. Hesperetin 7-O-glucoside is a potent human HMG-CoA reductase inhibitor and also effectively inhibits the growth of *Helicobacter pylori*. Antihypertensive effect .

HY-119977

APF	Reactive Oxygen Species	Others
APF is a fluorescence probe that can selectively, and dose dependently detect certain species among ROS and that are highly resistant to autoxidation. APF can be used in enzymatic and cellular systems .

HY-44157

ALS-I	Biochemical Assay Reagents	Neurological Disease
ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain .

HY-137662

5'-Phosphoguanylyl-(3',5')-guanosine pGpG	Others	Metabolic Disease
5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids .

HY-W012145

TMPD dihydrochloride	Others	Metabolic Disease
TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases . TMPD dihydrochloride is also a complex IV substrate .

HY-D0162

Malachite green hemioxalate 1 Publications Verification	IKK NF-κB Apoptosis	Cancer
Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo .

HY-P2295

Dabcyl-KTSAVLQSGFRKME-Edans TFA 1 Publications Verification	SARS-CoV	Others
Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-129217

Naringinase	Glucosidase	Others
Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase. Naringinase has wide occurrence in nature. Naringinase can be used in the biotransformation of steroids, antibiotics, and mainly on glycosides hydrolysis .

HY-143450

Tyrosinase-IN-3	Tyrosinase	Others
Tyrosinase-IN-3 (compound 54) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-3 has the potential for the research of skin whitening agents and food preservatives .

HY-143451

Tyrosinase-IN-4	Tyrosinase	Others
Tyrosinase-IN-4 (compound 34) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-4 has the potential for the research of skin whitening agents and food preservatives .

HY-143448

Tyrosinase-IN-1	Tyrosinase	Others
Tyrosinase-IN-1 (compound 90) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-1 has the potential for the research of skin whitening agents and food preservatives .

HY-143449

Tyrosinase-IN-2	Tyrosinase	Others
Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives .

HY-E70130

Snailase, Snail gastrointestinal	Others	Others
Snailase, Snail gastrointestinal is an enzyme mixture composed of more than 20 enzymes, which is often used for enzymatic hydrolysis of purified flavonoid glycosides. Snailase can be obtained from the digestive tract and includes cellulase, sucrase, hemicellulase, pectinase, polygalacturonase, protease, etc .

HY-23789

2′-O-(2-Methoxyethyl)guanosine 2'-O-MOE-rG	Nucleoside Antimetabolite/Analog	Others
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .

HY-150978

DDAO-C6	Fluorescent Dye	Others
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .

HY-P2296

Abz-FRLKGGAPIKGV-EDDNP TFA	Fluorescent Dye	Others
Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-D1376A

Sulfo-Cyanine5.5 amine	Fluorescent Dye	Others
Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .

HY-W007926

2-Oxobutanoic acid

Endogenous Metabolite Others

2-Oxobutanoic acid is a product in the enzymatic cleavage of cystathionine.

2-Oxobutanoic acid	Endogenous Metabolite	Others
2-Oxobutanoic acid is a product in the enzymatic cleavage of cystathionine.

HY-113080

N-Acetylornithine 1 Publications Verification	Endogenous Metabolite	Others
N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

HY-N3169

Nyasicol

(+)-Nyasicol
Others Others

Nyasicol ((+)-Nyasicol) is an enzymatic (β-glucosidase) hydrolysis product of Compound 3 .
HY-160473

TAM557

ADC Cytotoxin Microtubule/Tubulin Cancer

TAM557 is a cytotoxic tubulysin compound that can be used in enzymatic conjugation reactions .

Nyasicol (+)-Nyasicol	Others	Others
Nyasicol ((+)-Nyasicol) is an enzymatic (β-glucosidase) hydrolysis product of Compound 3 .

TAM557	ADC Cytotoxin Microtubule/Tubulin	Cancer
TAM557 is a cytotoxic tubulysin compound that can be used in enzymatic conjugation reactions .

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-N7264S

7α-Hydroxycholesterol-d7	Isotope-Labeled Compounds
7α-Hydroxycholesterol-d₇ is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2][3].

HY-116284

Methyl β-D-glucopyranoside

Methyl β-D-glucoside
Others Others

Methyl β-D-glucopyranoside is used to synthesize natural glycophenolics via enzymatic caffeoylation .

Methyl β-D-glucopyranoside Methyl β-D-glucoside	Others	Others
Methyl β-D-glucopyranoside is used to synthesize natural glycophenolics via enzymatic caffeoylation .

HY-120742

MMG-0358	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
MMG-0358 is a potent IDO1 inhibitor. MMG-0358 shows IC₅₀ values of 2 nM in a cellular assay on mIDO1, 80 nM in a cellular assay on hIDO1, 330 nM in an enzymatic assay on hIDO1 at pH 6.5, and 71 nM in an enzymatic assay on hIDO1 at pH 7.4 .

HY-112261

CDK12-IN-3

CDK Cancer

CDK12-IN-3 is a potent and selective CDK12 inhibitor with an IC₅₀ of 491 nM in enzymatic assay.
HY-145882

BOD-NH-NP

Fluorescent Dye Others

BOD-NH-NP is an activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway .

CDK12-IN-3	CDK	Cancer
CDK12-IN-3 is a potent and selective CDK12 inhibitor with an IC₅₀ of 491 nM in enzymatic assay.

BOD-NH-NP	Fluorescent Dye	Others
BOD-NH-NP is an activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway .

HY-Y0351

Phenylthiourea Phenylthiocarbamide
Phenylthiourea (Phenylthiocarbamide) is an inhibitor of phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (K_i: 0.21?μM) .

HY-12070

DPH 4 Publications Verification	Bcr-Abl	Cancer
DPH is a potent cell permeable c-Abl activator, which displays potent enzymatic and cellular activity in stimulating c-Abl activation.

HY-B1654

Flavin adenine dinucleotide FAD	Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B1654A

Flavin adenine dinucleotide disodium salt FAD disodium salt; FAD-Na2	Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-111789

Subasumstat 5+ Cited Publications TAK-981	E1/E2/E3 Enzyme	Inflammation/Immunology Cancer
Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities .

HY-113043

Galactonic acid	Endogenous Metabolite	Others
Galactonic acid is a sugar acid that is a metabolic breakdown product of galactose. Galactose dehydrogenase is responsible for converting galactose to galactonolactone, which then spontaneously or enzymatically converts to galactonic acid .

HY-P2893

Creatinase, Actinobacteria Creatine amidohydrolase	Endogenous Metabolite	Others
Creatinase, Actinobacteria (Creatine amidohydrolase) is a hydrolase that catalyzes the hydrolysis of creatine into sarcosine and urea, and plays an important role in the enzymatic determination of creatinine concentration .

HY-E70104

α-Rhamnosidase

Others Others

α-Rhamnosidase is a glycoside hydrolase. α-Rhamnosidase is able to finish the enzymatic de-glycosylation of many nature flavone glycosides .

α-Rhamnosidase	Others	Others
α-Rhamnosidase is a glycoside hydrolase. α-Rhamnosidase is able to finish the enzymatic de-glycosylation of many nature flavone glycosides .

HY-N6821

2-O-α-D-Glucopyranosyl-L-ascorbic Acid	Others	Cancer
2-O-α-D-Glucopyranosyl-L-ascorbic Acid is a glucoside derivative of ascorbic acid, shows anti-cancer activity after enzymatic hydrolysis to ascorbic acid .

HY-113080S

N-Acetylornithine-d2	Isotope-Labeled Compounds Endogenous Metabolite
N-Acetylornithine-d₂ is the deuterium labeled Melengestrol. N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

HY-157438A

pppApA sodium	Others	Metabolic Disease
pppApA sodium is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA sodium is formed by conjugation between two molecules of ATP .

HY-157438

pppApA	Others	Metabolic Disease
pppApA is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA is formed by conjugation between two molecules of ATP .

HY-12695B

Guanosine 5'-triphosphate trisodium salt hydrate 5'-GTP trisodium salt hydrate	Endogenous Metabolite DNA/RNA Synthesis	Others
5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

HY-P2237

Boc-Leu-Gly-Arg-AMC	Amino Acid Derivatives	Endocrinology
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays .

HY-B0866

Ametryn	Others	Metabolic Disease
Ametryn, a member of the Triazine chemical family, is a herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is effective against annual broadleaf weeds and grasses .

HY-P4399

Z-Gly-Gly-Leu-AMC

Bacterial ClpP Others

Z-Gly-Gly-Leu-AMC is the substrate of ClpP1 and ClpP2, to detect the enzymatic activity in the presence of the activating peptide Z-Leu-Leu .

HY-E70101

α-Glucuronidase	Others	Others
α-Glucuronidase plays an essential role in the full enzymatic hydrolysis of hemicellulose. α-Glucuronidase cleaves the attached MeGlcA moiety from the xylose .

Cat. No.	Product Name

HY-L149

Membrane Protein-targeted Compound Library

6853 compounds

A membrane protein is a protein molecule that is attached to or associated with the membrane of a cell or an organelle. Membrane proteins can be classified into two groups based on how the protein is associated with the membrane: integral membrane proteins and peripheral membrane proteins. In humans, about 30% genome encodes membrane proteins. Membrane proteins perform a variety of functions vital to the survival of organisms, for example, signal transduction, molecules or ion transportation, enzymatic catalysis, and intercellular communication. Membrane proteins also play important roles in drug discovery. As reported, more than 60% of current drug targets are membrane proteins.

MCE supplies a unique collection of 6853 compounds targeting a variety of membrane proteins. MCE Membrane Protein-targeted Compound Library can be used for membrane protein-focused screening and drug discovery.

HY-L050

Ubiquitination Compound Library

286 compounds

Protein ubiquitination is an enzymatic post-translational modification in which an ubiquitin protein is attached to a substrate protein. Ubiquitination involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. Ubiquitination affects cellular processes such as apoptosis, cell cycle, DNA damage repair, and membrane transportation, etc. by regulating the degradation of proteins (via the proteasome and lysosome), altering the cellular localization of proteins, affecting proteins activity, and promoting or preventing protein-protein interactions. Deregulation of ubiquitin pathway leads to many diseases such as neurodegeneration, cancer, infection and immunity, etc.

MCE offers a unique collection of 286 small molecule modulators with biological activity used for ubiquitination research. Compounds in this library target the key enzymes in ubiquitin pathway. MCE Ubiquitination Compound Library is a useful tool for the research of ubiquitination regulation and the corresponding diseases.

Cat. No.	Product Name	Type

HY-D0162

Malachite green hemioxalate 1 Publications Verification	Fluorescent Dyes/Probes
Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo .

HY-15914

DHBS DCHBS	Chromogenic Substrates
DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions.

HY-D1706

AMCA-6-dUTP

Fluorescent Dyes/Probes

AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA .

HY-150978

DDAO-C6	Fluorescent Dyes/Probes
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .

HY-D1376A

Sulfo-Cyanine5.5 amine

Fluorescent Dyes/Probes

Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .

HY-D1647

7-Hydroxycoumarinyl-γ-linolenate	Chromogenic Substrates
7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A₂ (cPLA₂) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA₂ .

HY-D1811

Vari Fluor 555-dUTP VF 555-dUTP	Dyes
Vari Fluor 555-dUTP (VF 555-dUTP) can be used to produce biotinylated DNA probes in a variety of assay applications by enzymatic incorporation into DNA/cDNA, replacing its natural counterpart, dTTP .

HY-D1810

Sulfo-Cy3-E-dUTP	Dyes
Sulfo-Cy3-E-dUTP is enzymatically incorporated into DNA/cDNA as a substitute for its natural counterpart, dTTP. Sulfo-Cy3-E-dUTP can be used to produce biotinylated DNA probes for various detection applications .

HY-D1812

Vari Fluor 488-dUTP VF 488-dUTP	Dyes
Vari Fluor 488-dUTP (VF 488-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1813

Vari Fluor 594-dUTP VF 594-dUTP	Dyes
Vari Fluor 594-dUTP (VF 594-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1814

Vari Fluor 640-dUTP VF 640-dUTP	Dyes
Vari Fluor 640-dUTP (VF 640-dUTP) is enzymatically incorporated into DNA/cDNA and can replace its natural counterpart, dTTP. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1022

Biotin-16-dUTP Biotin-16-deoxyuridine-5'-triphosphate	Fluorescent Dyes/Probes
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1022A

Biotin-16-dUTP trisodium Biotin-16-deoxyuridine-5'-triphosphate trisodium	Fluorescent Dyes/Probes
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-W154295

Purple-β-D-Gal	Fluorescent Dyes/Probes
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .

Cat. No.	Product Name	Type

HY-129217

Naringinase	Biochemical Assay Reagents
Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase. Naringinase has wide occurrence in nature. Naringinase can be used in the biotransformation of steroids, antibiotics, and mainly on glycosides hydrolysis .

HY-23789

2′-O-(2-Methoxyethyl)guanosine 2'-O-MOE-rG	Biochemical Assay Reagents
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .

HY-E70003

Glutamate dehydrogenase	Biochemical Assay Reagents
Glutamate dehydrogenase is an enzyme in both prokaryotes and eukaryotic mitochondria. Glutamate dehydrogenase can be used for the enzymatic determination of ammonia, alpha-ketoglutaric acid, L-glutamate and urease .

HY-W099563

4-Nitrophenyl stearate

Biochemical Assay Reagents

4-Nitrophenyl stearate, which is an ester formed by the condensation of stearic acid and 4-nitrophenol, is commonly used as a substrate for enzymatic assays, where the hydrolysis of ester bonds by esterase and lipase can be measured by absorbance or ratio In addition, 4-Nitrophenyl stearate has been used as a model compound to study the enzymatic activity and selectivity of lipases and esterases from various sources. The long hydrophobic tail of the molecule makes it suitable for use in lipophilic Good solubility in the environment makes it a useful probe for studying lipid metabolism.

HY-E70067

GlcNAc 1-P uridyltransferase (PmGlmU)	Biochemical Assay Reagents
GlcNAc 1-P uridyltransferase (PmGlmU) catalyzes high efficient synthesis of UDP-GlcNAc from GlcNAc-1-P and UTP. GlcNAc 1-P uridyltransferase (PmGlmU) is used to break down the pyrophosphate formed in the PmGlmU reaction to inorganic phosphate to shift the equilibrium of the coupled enzymatic reactions towards the formation of UDP-GlcNA .

HY-P2753

Sucrose phosphorylase

Biochemical Assay Reagents

Sucrose phosphorylase is a bacterial transglucosidase that catalyzes the conversion of sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose. The glucosylated Sucrose phosphorylase can also be hydrolyzed into α-D-glucose, or transfer the glucoyl to the hydroxyl group of the receptor, and then decomposed into new α-D-glucoside products. The enzymatic activity of base phosphorylase to substrate and product is weak .

HY-W127719

Photobiotin acetate

Biochemical Assay Reagents

Photobiotin (acetate)It is a biological probe used to study biochemical processes such as protein interactions and enzymatic reactions. It is a molecule containing a photosensitive group, which can be combined with specific target molecules (such as proteins, nucleic acids, etc.) through photochemical cross-linking technology, so as to realize the labeling and detection of these molecules. During the photosensitive crosslinking process, Photobiotin (acetate)Can participate in the formation of covalent bonds and form stable compounds. In addition, the compound also has high biocompatibility and biological activity, so it is widely used in the field of biomedical research, such as enzymatic research, proteomics, western blotting and other aspects. Photobiotin (acetate) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-W088070A

Agarose,Low melting point

Biochemical Assay Reagents

Agarose,Low melting point is a kind of agarose, a kind of polysaccharide that can be derived from seaweed. It is commonly used in molecular biology and biochemistry to isolate and purify DNA and RNA fragments. Agarose,Low melting point is a low melting point agarose, which is suitable for the recovery of large DNA fragments and enzymatic reactions in gels and other applications. In addition, it has been used in various techniques, such as pulsed field gel electrophoresis and capillary electrophoresis for analyzing genetic material.

HY-133971

Cholesterol 5α,6α-epoxide

5α,6α-Epoxycholesterol

Biochemical Assay Reagents

Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.

HY-W010934

3β,5α,6β-Trihydroxycholestane

Biochemical Assay Reagents

3β,5α,6β-Trihydroxycholestane is a steroid that occurs naturally in the body and is also found in certain foods. It belongs to a class of compounds known as cholestanes, which are closely related to the better known cholesterol. This particular compound is formed from cholesterol through a series of enzymatic reactions in the liver and other organs. It has been studied for its potential health benefits, including its ability to reduce inflammation and oxidative stress in the body. Some research suggests that it may also play a role in regulating blood sugar levels and improving insulin sensitivity. Despite these potential benefits, 3β,5α,6β-Trihydroxycholestane is not widely used as a supplement or medicine due to its relatively low content, focus on natural resources and limited research. However, researchers continue to investigate its potential uses and effects on human health.

Cat. No.	Product Name	Target	Research Area

HY-P2295

Dabcyl-KTSAVLQSGFRKME-Edans TFA 1 Publications Verification	SARS-CoV	Others
Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-P10050

Calpain substrate

Peptides Others

Calpain substrate is the membrane non-permeable fluorogenic calpain substrate and can be used in Calpain enzymatic activity assay .
HY-P2344

HIV Protease Substrate 1

HIV Protease Infection

HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .
HY-P2344A

HIV Protease Substrate 1 TFA

HIV Protease Infection

HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

HY-P3733

Big Endothelin-1 (22-38), human	Peptides	Cardiovascular Disease
Big Endothelin-1 (22-38), human is derived from human, is the 22-38 fragment of Big Endothelin-1 (ET-1) (1-38). Big ET-1 (1-38) is a propeptide of ET-1, which has potent and long-lasting vasoconstrictor effects, equips a specific enzymatic cleavage of the 38 amino acid chain to form ET-1 (1-21) and the C-terminal fragment Big ET-1 (22-38) .

HY-P2296

Abz-FRLKGGAPIKGV-EDDNP TFA	Fluorescent Dye	Others
Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-P3305

NBD-LLLLpY

Peptides Others

NBD-LLLLpY is an enzymatically forming intranuclear peptide for selectively killing human induced pluripotent stem cells.

HY-W140249

Angiogenin Fragment (108-123)	Peptides	Cardiovascular Disease
Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin .

HY-P4491

Suc-Leu-Leu-Val-Tyr-pNA

Peptides Others

Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .
HY-P2237

Boc-Leu-Gly-Arg-AMC

Amino Acid Derivatives Endocrinology

Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays .
HY-P4399

Z-Gly-Gly-Leu-AMC

Bacterial ClpP Others

Z-Gly-Gly-Leu-AMC is the substrate of ClpP1 and ClpP2, to detect the enzymatic activity in the presence of the activating peptide Z-Leu-Leu .

HY-P5990

Prostate Specific Antigen Substrate	PSMA	Cancer
Prostate Specific Antigen Substrate is a prostate specific antigen (PSA) fluorescent substrate. Prostate Specific Antigen Substrate can be used for detect enzymatic activity of PSA .

HY-P10043

MMP-1 Substrate	Peptides	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity .

HY-P4313

Asp-Val	Peptides	Others
Asp-Val is a dipeptide formed from L-alpha-aspartyl and L-valine residues. Asp-Val has a role as a metabolite. Asp-Val can be isolated from an enzymatic hydrolysate of food proteins .

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Endogenous Metabolite	Others
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-P3437

Dabcyl-KTSAVLQSGFRKM-Glu(Edans)-NH2	Virus Protease	Others
Dabcyl-KTSAVLQSGFRKM-Glu(Edans)-NH2 is a fluorogenic peptide, as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKM-Glu(Edans)-NH2 can be used for researching 2019-nCoV (COVID-19) infection.

HY-101399A

γ-Glu-Phe TFA γ-Glutamylphenylalanine TFA	Endogenous Metabolite	Others
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-103293

Lys-Bradykinin Kallidin (380-389) (human, porcine, bovine)	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin, a kind of kallidin and bradykinin receptor ligand, can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin, also a vasodilator, can widen blood vessels and increase blood flow. Lys-Bradykinin involves in vascular regulation, inflammation and pain sensation .

HY-P3632

[DAla2, DArg6] Dynorphin A, (1-13) (porcine) DADAD	Opioid Receptor	Neurological Disease Metabolic Disease
[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes .

HY-P5815

GLP-1 (1-36) amide (human, rat) Glucagon-like Peptide 1 (1-36) amide (human, rat)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .

HY-P5815A

GLP-1 (1-36) amide (human, rat) (TFA) Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7264

7α-Hydroxycholesterol	Classification of Application Fields Animals Source classification Metabolic Disease Disease Research Fields Steroids	Others
7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation .

HY-125130

Hesperetin 7-O-glucoside	Structural Classification Flavonoids Classification of Application Fields Flavonones Source classification Phenols Polyphenols Metabolic Disease Plants Umbelliferae Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray	HMG-CoA Reductase (HMGCR) Bacterial
Hesperetin 7-O-glucoside is produced by the enzymatic conversion of Hesperidin. Hesperetin 7-O-glucoside is a potent human HMG-CoA reductase inhibitor and also effectively inhibits the growth of *Helicobacter pylori*. Antihypertensive effect .

HY-129217

Naringinase	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Glucosidase
Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase. Naringinase has wide occurrence in nature. Naringinase can be used in the biotransformation of steroids, antibiotics, and mainly on glycosides hydrolysis .

HY-W007926

2-Oxobutanoic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Oxobutanoic acid is a product in the enzymatic cleavage of cystathionine.

HY-113080

N-Acetylornithine 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

HY-N3169

Nyasicol (+)-Nyasicol	Curculigo orchioides Gaertn. Structural Classification Source classification Phenols Polyphenols Plants Amaryllidaceae	Others
Nyasicol ((+)-Nyasicol) is an enzymatic (β-glucosidase) hydrolysis product of Compound 3 .

HY-B1654

Flavin adenine dinucleotide FAD	Cardiovascular Disease Natural Products Human Gut Microbiota Metabolites other families Microorganisms Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B1654A

Flavin adenine dinucleotide disodium salt FAD disodium salt; FAD-Na2	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-113043

Galactonic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Galactonic acid is a sugar acid that is a metabolic breakdown product of galactose. Galactose dehydrogenase is responsible for converting galactose to galactonolactone, which then spontaneously or enzymatically converts to galactonic acid .

HY-12695B

Guanosine 5'-triphosphate trisodium salt hydrate 5'-GTP trisodium salt hydrate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite DNA/RNA Synthesis
5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

HY-W007926R

2-Oxobutanoic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite	Endogenous Metabolite
2-Oxobutanoic acid (Standard) is the analytical standard of 2-Oxobutanoic acid. This product is intended for research and analytical applications. 2-Oxobutanoic acid is a product in the enzymatic cleavage of cystathionine.

HY-N0598

Ginsenoside F1 20(S)-Ginsenoside F1	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer	Cytochrome P450 Endogenous Metabolite
Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity.

HY-N11692

9-Hydroxyoctadecanoic acid 9-Hydroxystearic acid; 9-HSA	Apocynaceae Structural Classification Strophanthus sarmentosus DC. Ketones, Aldehydes, Acids Source classification Plants	HDAC
9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity .

HY-W010737

Guanosine-5'-triphosphate disodium salt 5 Publications Verification 5'-GTP disodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Guanosine-5'-triphosphate disodium salt (5'-GTP trisodium salt) is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA .

HY-N0640

Kuromanin chloride 5 Publications Verification Chrysontemin; Cyanidin 3-O-glucoside chloride	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Moraceae Anthocyans Flavonoids Microorganisms Phenols Polyphenols Disease Research Fields Morus alba Linn.	CD38
Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .

HY-126791

Methylmalonyl-CoA Isosuccinyl coenzyme A; Methylmalonyl coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-B0456

Riboflavin Vitamin B2; E101	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial
Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-126791A

Methylmalonyl-CoA tetralithium Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-112653A

(±)8-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of Arachidonic acid (HY-109590). The biological activity of (±)8-HETE is likely to resemble that of its constituent enantiomers (8(R)-HETE and 8(S)-HETE).

HY-101399A

γ-Glu-Phe TFA γ-Glutamylphenylalanine TFA	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-125773

β-cyano-L-Alanine Beta-cyano-l-alanine	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates . β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury .

HY-N0814B

Phytic acid hexasodium Inositol hexaphosphate hexasodium; SNF472	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

HY-113209

8-Isoprostaglandin F2α	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.

HY-N0814

Phytic acid 1 Publications Verification Inositol hexaphosphate; SNF472 free acid	Structural Classification Neurological Disease Classification of Application Fields Food Preservation Research Source classification Plants Endogenous metabolite Agricultural Research other families Microorganisms Ketones, Aldehydes, Acids Inflammation/Immunology Disease Research Fields	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-N10473

Pulcherriminic acid	Structural Classification Microorganisms Cyclopeptides	Bacterial Fungal
Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe ³⁺, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries .

HY-N0814A

Phytic acid dodecasodium hydrate 1 Publications Verification Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-141508

Flazin	Simaroubaceae Source classification Plants Indole Alkaloids Brucea javanica (L.) Merr.	Xanthine Oxidase NO Synthase
Flazin is a *non-enzymatic* protein glycation inhibitor, also inhibits peroxynitrite (ONOO ^-), with an IC₅₀ value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC₅₀ value of 71.99 μM for ONOO ^-. Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD)** inhibitor .

HY-113330

12S-HHT 1 Publications Verification 12(S)-HHTrE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Leukotriene Receptor Endogenous Metabolite
12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H₂ (PGH₂) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity .

HY-W010934

3β,5α,6β-Trihydroxycholestane	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Biochemical Assay Reagents
3β,5α,6β-Trihydroxycholestane is a steroid that occurs naturally in the body and is also found in certain foods. It belongs to a class of compounds known as cholestanes, which are closely related to the better known cholesterol. This particular compound is formed from cholesterol through a series of enzymatic reactions in the liver and other organs. It has been studied for its potential health benefits, including its ability to reduce inflammation and oxidative stress in the body. Some research suggests that it may also play a role in regulating blood sugar levels and improving insulin sensitivity. Despite these potential benefits, 3β,5α,6β-Trihydroxycholestane is not widely used as a supplement or medicine due to its relatively low content, focus on natural resources and limited research. However, researchers continue to investigate its potential uses and effects on human health.

Cat. No.	Product Name	Chemical Structure

HY-N7264S

7α-Hydroxycholesterol-d7
7α-Hydroxycholesterol-d₇ is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2][3].

HY-113080S

N-Acetylornithine-d2
N-Acetylornithine-d₂ is the deuterium labeled Melengestrol. N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

HY-16106S

Talazoparib-13C,d4
Talazoparib- ¹³C,d4 is ¹³C and deuterated labeled Talazoparib (HY-16106). Talazoparib is an orally active PARP 1/2 inhibitor with Ki values of 1.2 nM and 0.87 nM for inhibiting PARP1 and PARP2 enzymatic activities, respectively. Has anti-tumor activity.

HY-B0866S

Ametryn-13C,d3
Ametryn- ¹³C,d₃ is the ¹³C- and deuterium labeled Ametryn. Ametryn, a member of the Triazine chemical family, is a herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is effective against annual broadleaf weeds and grasses[1].

HY-B1654S

Flavin adenine dinucleotide-13C5 ammonium
Flavin adenine dinucleotide- ¹³C5 (FAD- ¹³C5) ammonium is ¹³C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B0091S

Adapalene-d3
Adapalene-d₃ is the deuterium labeled Adapalene. Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity[1][2][3].

HY-113209S1

8-iso Prostaglandin F2α-d9

8-iso Prostaglandin F2α-d₉ is the deuterium labeled 8-Isoprostaglandin F2α. 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.

HY-B1455S

Clindamycin-d3 hydrochloride

Clindamycin-d₃ (hydrochloride) is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2].

HY-B1455S1

Clindamycin-13C,d3

Clindamycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2][3].

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