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β-cyano-L-Alanine (Synonyms: Beta-cyano-l-alanine)

Cat. No.: HY-125773 Purity: ≥98.0%
Handling Instructions

β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.

For research use only. We do not sell to patients.

β-cyano-L-Alanine Chemical Structure

β-cyano-L-Alanine Chemical Structure

CAS No. : 6232-19-5

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Description

β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates[1]. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury[2].

In Vivo

β-cyano-L-Alanine (intraperitoneally; 50 mg/kg) abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult (postnatal age: 60 days) male C57BL/6J mice (25-30 g) gavage-fed with ethanol[2]
Dosage: 50 mg/kg
Administration: Intraperitoneally
Result: Abolished the protective effect of ethanol on cerebral I/R injury.
Molecular Weight

114.10

Formula

C₄H₆N₂O₂

CAS No.

6232-19-5

SMILES

N[[email protected]@H](CC#N)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 20.83 mg/mL (182.56 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.7642 mL 43.8212 mL 87.6424 mL
5 mM 1.7528 mL 8.7642 mL 17.5285 mL
10 mM 0.8764 mL 4.3821 mL 8.7642 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

β-cyano-L-AlanineBeta-cyano-l-alanineOthersInhibitorinhibitorinhibit

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β-cyano-L-Alanine
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