8-Isoprostaglandin F2α
Based on 1 Customer Validation
8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.
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- Reinheit : 99.9%
- CAS. Nr.: 27415-26-5
- Formel: C20H34O5
- Molecular Weight:354.48
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Speicherung:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
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Human Endogenous Metabolite |
Chemical Information
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CAS. Nr. 27415-26-5
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Appearance Solid
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Molecular Weight 354.48
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Formel C20H34O5
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Color White to off-white
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SMILES
CCCCC[C@H](O)/C=C/[C@@H]1[C@@H]([C@@H](O)C[C@H]1O)C/C=C\CCCC(O)=O
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Synonyms
8-iso-PGF2α
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : ≥ 100 mg/mL (282.10 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (247 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.8210 mL | 14.1052 mL | 28.2103 mL | 70.5258 mL |
| 5 mM | 0.5642 mL | 2.8210 mL | 5.6421 mL | 14.1052 mL | |
| 10 mM | 0.2821 mL | 1.4105 mL | 2.8210 mL | 7.0526 mL | |
| 15 mM | 0.1881 mL | 0.9403 mL | 1.8807 mL | 4.7017 mL | |
| 20 mM | 0.1411 mL | 0.7053 mL | 1.4105 mL | 3.5263 mL | |
| 25 mM | 0.1128 mL | 0.5642 mL | 1.1284 mL | 2.8210 mL | |
| 30 mM | 0.0940 mL | 0.4702 mL | 0.9403 mL | 2.3509 mL | |
| 40 mM | 0.0705 mL | 0.3526 mL | 0.7053 mL | 1.7631 mL | |
| 50 mM | 0.0564 mL | 0.2821 mL | 0.5642 mL | 1.4105 mL | |
| 60 mM | 0.0470 mL | 0.2351 mL | 0.4702 mL | 1.1754 mL | |
| 80 mM | 0.0353 mL | 0.1763 mL | 0.3526 mL | 0.8816 mL | |
| 100 mM | 0.0282 mL | 0.1411 mL | 0.2821 mL | 0.7053 mL |
8-Isoprostaglandin F2α Related Classifications
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