2. Lipids
  3. Eicosanoids
  4. Isoprostanes

Isoprostanes

Isoprostanes (16):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-113209
    8-Isoprostaglandin F2α 27415-26-5 99.9%
    8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.
    8-Isoprostaglandin F2α
  • HY-W346976
    8-Iso-15-keto prostaglandin E2 914804-63-0
    8-Iso-15-keto prostaglandin E2 is a fatty acyl.
    8-Iso-15-keto prostaglandin E2
  • HY-114599
    8-iso Prostaglandin A1 211186-29-7 98.33%
    8-iso Prostaglandin A1 is an active substrate for Arabidopsis thaliana OPR3 (AtOPR3), with a KM of 22 μM.
    8-iso Prostaglandin A1
  • HY-130304
    8-Isoprostaglandin E2 27415-25-4 98.31%
    8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A2 (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway.
    8-Isoprostaglandin E2
  • HY-137012
    8-iso Prostaglandin F1α 26771-96-0
    8-iso Prostaglandin F1α is an active compound.
    8-iso Prostaglandin F1α
  • HY-138244
    8-iso Prostaglandin F2β 177020-26-7
    8-iso Prostaglandin F2β (8-iso PGF2β) is a biomarker for assessing oxidative stress, and its content in serum can indirectly reflect the level of oxidative stress.
    8-iso Prostaglandin F2β
  • HY-125626
    8-iso-15-keto Prostaglandin F2α 191919-01-4
    8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a partial agonist for Thromboxane receptor (TP), which exhibits a vasoconstrictor efficacy with a pD2 of 5.8. 8-iso-15-keto Prostaglandin F2α mediates a weak relaxation of rats aorta rings at high concentration.
    8-iso-15-keto Prostaglandin F2α
  • HY-114892
    15-A2t-Isoprostane 474391-66-7
    15-A2t-Isoprostane (8-iso Prostaglandin A2) is an isoprostaglandin produced by the non-enzymatic oxidation of arachidonic acid.
    15-A2t-Isoprostane
  • HY-113209A
    ent-8-Iso-15(S)-prostaglandin F2α 214748-66-0
    Ent-8-Iso-15(S)-prostaglandin F2α is an isomer of 8-Isoprostaglandin F2α, with a better inhibiting activity in the whole blood platelet aggregation inhibition assay.
    ent-8-Iso-15(S)-prostaglandin F2α
  • HY-118094
    8-iso Prostaglandin E1 21003-46-3
    8-iso Prostaglandin E1 (Ovinonic acid; 8-iso-PGE1) is a spasmodic agent in canine pulmonary veins and can also cause vasodilation.
    8-iso Prostaglandin E1
  • HY-N12119
    ent-Prostaglandin F2α 54483-31-7
    ent-Prostaglandin F2α is the opposite enantiomer of PGF2α. ent-Prostaglandin F2α can be found in urine.
    ent-Prostaglandin F2α
  • HY-118465
    ent-Prostaglandin E2 65085-69-0
    ent-Prostaglandin E2 (ent-PGE2) is an enantiomer of PGE2 (HY-101952). unlike PGE2, ent-PGE2 is a poor substrate for 15-hydroxyprostaglandin dehydrogenase.
    ent-Prostaglandin E2
  • HY-114593
    ent-8-iso Prostaglandin F2α 159812-83-6
    ent-8-iso Prostaglandin F2α (ent-15-F2t-IsoP) is a potent vasoconstrictor of porcine retina and cerebral microvessels with EC50 values of 30.6 and 53.5 nM, respectively.
    ent-8-iso Prostaglandin F2α
  • HY-W353470
    2,3-Dinor-8-iso prostaglandin F 2α 221664-05-7
    2,3-Dinor-8-iso prostaglandin F₂α (2,3-Dinor-8-isoPGF2α) is the major β-oxidation metabolite of 8-iso-prostaglandin F₂α. 2,3-Dinor-8-iso prostaglandin F₂α serves as a biomarker to evaluate the in vivo production of 8-iso-prostaglandin F₂α and the level of lipid peroxidation. 2,3-Dinor-8-iso prostaglandin F₂α is promising for research of oxidative stress-related diseases such as arteriosclerosis and diabetes.
    2,3-Dinor-8-iso prostaglandin F 2α
  • HY-W408869
    8-iso-13,14-dihydro-15-keto Prostaglandin F2α 191919-02-5
    8-iso-13,14-dihydro-15-keto Prostaglandin F2α is an oxidative metabolite of 8-iso-prostaglandin F2α (HY-113209). 8-iso-13,14-dihydro-15-keto Prostaglandin F2α can be used in the study of oxidative stress-related diseases.
    8-iso-13,14-dihydro-15-keto Prostaglandin F2α
  • HY-116008
    8-iso Prostaglandin F3α 7045-31-0
    8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 μM.
    8-iso Prostaglandin F3α