7045-31-0
Chemical Structure
8-iso Prostaglandin F3α
Synonym(s): 8-epi PGF3α; 8-iso PGF3α
- CAS No.: 7045-31-0
- Formula:C20H32O5
- Molecular Weight:352.47
IUPAC Name: (Z)-7-((1S,2R,3R,5S)-3,5-dihydroxy-2-((S,1E,5Z)-3-hydroxyocta-1,5-dien-1-yl)cyclopentyl)hept-5-enoic acid
InChIKey: SAKGBZWJAIABSY-PJCXKLBTSA-N
SMILES: O[C@@H]1[C@H]([C@H]([C@@H](C1)O)/C=C/[C@H](C/C=C\CC)O)C/C=C\CCCC(O)=O
Biological Activity: 8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 μM.
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8-iso Prostaglandin F3α | 8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 μM. | |||||||||||||||||||||
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