1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. 8-Isoprostaglandin E2

8-Isoprostaglandin E2  (Synonyms: iPE2-III)

Cat. No.: HY-130304 Purity: ≥99.0%
COA Handling Instructions

8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A2 (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway.

For research use only. We do not sell to patients.

8-Isoprostaglandin E2 Chemical Structure

8-Isoprostaglandin E2 Chemical Structure

CAS No. : 27415-25-4

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Based on 1 publication(s) in Google Scholar

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Description

8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A2 (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway[1][2].

Molecular Weight

352.47

Formula

C20H32O5

CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C(C[C@H]1O)=O)C/C=C\CCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

References
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8-Isoprostaglandin E2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
8-Isoprostaglandin E2
Cat. No.:
HY-130304
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