2,3-Dinor-8-iso prostaglandin F 2α
2,3-Dinor-8-iso prostaglandin F₂α (2,3-Dinor-8-isoPGF2α) is the major β-oxidation metabolite of 8-iso-prostaglandin F₂α. 2,3-Dinor-8-iso prostaglandin F₂α serves as a biomarker to evaluate the in vivo production of 8-iso-prostaglandin F₂α and the level of lipid peroxidation. 2,3-Dinor-8-iso prostaglandin F₂α is promising for research of oxidative stress-related diseases such as arteriosclerosis and diabetes.
For research use only. We do not sell to patients.
- CAS No.: 221664-05-7
- Formula: C18H30O5
- Molecular Weight:326.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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8-Iso-16-cyclohexyl-tetranor prostaglandin E2
Biological Activity
Description
Chemical Information
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CAS No. 221664-05-7
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Molecular Weight 326.43
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Formula C18H30O5
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SMILES
OC(C/C=C\C[C@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O
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Synonyms
2,3-Dinor-8-isoPGF2α
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Liang Y, et al. Quantification of 8-iso-prostaglandin-F(2alpha) and 2,3-dinor-8-iso-prostaglandin-F(2alpha) in human urine using liquid chromatography-tandem mass spectrometry. Free Radic Biol Med. 2003 Feb 15;34(4):409-18. [Content Brief]
[2]. Chiabrando C, et al. Identification and measurement of endogenous beta-oxidation metabolites of 8-epi-Prostaglandin F2alpha. J Biol Chem. 1999 Jan 15;274(3):1313-9. [Content Brief]
[3]. Roberts LJ 2nd, et al. Identification of the major urinary metabolite of the F2-isoprostane 8-iso-prostaglandin F2alpha in humans. J Biol Chem. 1996 Aug 23;271(34):20617-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2,3-Dinor-8-iso prostaglandin F 2α Related Classifications
HY-W353470 Related Classifications
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