8-Isoprostaglandin F2α-d9
8-iso Prostaglandin F2α-d9 is the deuterium labeled 8-Isoprostaglandin F2α. 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.
For research use only. We do not sell to patients.
- Formula: C20H25D9O5
- Molecular Weight:363.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled CAS 27415-26-5
-
Molecular Weight 363.54
-
Formula C20H25D9O5
-
SMILES
O[C@@H]([C@@H]1C/C=C\CCCC(O)=O)C[C@@H]([C@H]1/C=C/[C@H](CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])O)O
-
Synonyms
8-iso-PGF2α-d9
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (275.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7507 mL | 13.7536 mL | 27.5073 mL | 68.7682 mL |
| 5 mM | 0.5501 mL | 2.7507 mL | 5.5015 mL | 13.7536 mL | |
| 10 mM | 0.2751 mL | 1.3754 mL | 2.7507 mL | 6.8768 mL | |
| 15 mM | 0.1834 mL | 0.9169 mL | 1.8338 mL | 4.5845 mL | |
| 20 mM | 0.1375 mL | 0.6877 mL | 1.3754 mL | 3.4384 mL | |
| 25 mM | 0.1100 mL | 0.5501 mL | 1.1003 mL | 2.7507 mL | |
| 30 mM | 0.0917 mL | 0.4585 mL | 0.9169 mL | 2.2923 mL | |
| 40 mM | 0.0688 mL | 0.3438 mL | 0.6877 mL | 1.7192 mL | |
| 50 mM | 0.0550 mL | 0.2751 mL | 0.5501 mL | 1.3754 mL | |
| 60 mM | 0.0458 mL | 0.2292 mL | 0.4585 mL | 1.1461 mL | |
| 80 mM | 0.0344 mL | 0.1719 mL | 0.3438 mL | 0.8596 mL | |
| 100 mM | 0.0275 mL | 0.1375 mL | 0.2751 mL | 0.6877 mL |
8-Isoprostaglandin F2α-d9 Related Classifications
HY-113209S1 Related Classifications
Powered by Bioz