CDK4/6-IN-12
Based on 1 Customer Validation
CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 99.76%
- CAS No.: 2445205-24-1
- Formula: C12H10N6
- Molecular Weight:238.25
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
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CDK4 592.3 nM (IC50) |
CDK6 3090 nM (IC50) |
Chemical Information
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CAS No. 2445205-24-1
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Appearance Solid
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Molecular Weight 238.25
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Formula C12H10N6
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Color Light yellow to green yellow
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SMILES
CC1=CN2C3=NC(N)=NC=C3C(C)=C(C2=N1)C#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)